Results 251 to 260 of about 12,002 (336)

Non-Viral CRISPR carriers: transient delivery with lasting effects. [PDF]

Drug Deliv
Lummerstorfer M, Lächelt U.
europepmc   +1 more source

Hydrogels for Cancer Immunotherapy: Strategies From Construction to Application

MedComm, Volume 7, Issue 2, February 2026.
Hydrogels offer an innovative platform for cancer immunotherapy. Through tailorable crosslinking strategies, they form customizable drug delivery platforms that address diverse therapeutic requirements by loading specific immunotherapeutic agents. These systems demonstrate significant clinical potential for precise tumor immunotherapy.
Xiaohua Chen, Shan Wu, Yueyang Zhang, Lilu Feng, Yang Chen, Xuzhao Yang, Ke Men, Jiuqun Zhu, Ming Li   +8 more
wiley   +1 more source

Optimization of lipid nanoparticles loaded with ribonucleoprotein-oligonucleotide complexes for in vivo delivery of a CRISPR/Cas9 system targeting hepatitis B virus. [PDF]

Virus Res
Akhter R, Kitab B, Kayesh MEH, Shimizu R, Onuma H, Yamamoto N, Ogawa S, Sugiyama M, Tanaka Y, Sato Y, Kohara M, Tsukiyama-Kohara K.   +11 more
europepmc   +1 more source

Oligodendrocyte: Development, Plasticity, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
The oligodendrocyte lineage and its roles in development, plasticity, and CNS homeostasis have been shown to have the potential to treat neurological diseases. However, the main obstacles to clinical translation, particularly in terms of BBB challenges and precise delivery.
Qiong Xiang, Ruo‐Lan Shi, You‐Xia Huang, Li‐Ni Liu, Jia‐Sheng Tao, Xian‐Hui Li, Xiao‐Da Li   +6 more
wiley   +1 more source

The Gastrointestinal Tract: A Unique Battlefield for Bioengineering Delivery Platforms. [PDF]

Bioengineering (Basel)
Ma T, Sun S.
europepmc   +1 more source

Toward Dual‐Function Nanoparticle Platforms for Arboviral Diagnostics and Vaccines: Advances, Challenges, and Future Prospects

Nano Select, Volume 7, Issue 2, February 2026.
This review explores nanoparticle (NP)‐based biosensors and nanovaccine platforms for arboviral infections, highlighting their design, performance, and translational potential. By comparing case studies across viruses, it identifies gold‐standard nanomaterials such as gold NPs (AuNPs), zinc oxide NPs (ZnONPs), molybdenum disulfide (MoS2) nanocomposites,
Peyman Halvaeikhanekahdani, Sajad Zandi, Qadeer Ahmad, Hadiseh Payravand   +3 more
wiley   +1 more source

In vivo engineering of CAR-T cells: delivery strategies and clinical translation. [PDF]

Biomark Res
Gao Y, Hu J, An N, Wen X, Li C.
europepmc   +1 more source

Immunostimulatory and Immunodynamic Modeling Analysis to Determine a Plausible Starting Dose of mRNA‐4359 for Use in First‐In‐Human Trials

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT The investigational antigen‐specific immunotherapy mRNA‐4359 is a lipid nanoparticle–encapsulated mRNA‐based immunotherapy that encodes for the immunogenic indoleamine 2,3‐dioxygenase (IDO) and programmed death‐ligand 1 (PD‐L1) antigens.
Stephen A. Greene, Madhav Channavazzala, Bhairav Paleja, Harshbir Singh Sandhu, Rukmini Kumar, Husain Attarwala, Linh Van, Min Liang   +7 more
wiley   +1 more source

Replacing Helper Lipids With Cationic Lipids Enhances mRNA Lipid Nanoparticles Stability in Solution. [PDF]

Adv Sci (Weinh)
Chen R, Xu L, Zhang N, Yu H, Wang X, Zhai J, Whelan F, Elliott P, Zhao CX.   +8 more
europepmc   +1 more source

‘Exosomes’: The Hype, the Chasm, and Beyond

Journal of Extracellular Biology, Volume 5, Issue 2, February 2026.
Natasa Zarovni, Konstantin Glebov
wiley   +1 more source