Results 301 to 310 of about 12,002 (336)
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Abstract Lipid nanoparticles (LNPs) have emerged as effective delivery vehicles for nucleic acids. However, conventional LNP formulations face several limitations, including poor endosomal escape and ApoE‐mediated liver tropism. Here, a novel class of LNPs, endogenous corticosteroid‐derived LNPs (cortico LNPs), is introduced in which ...
Ivan Isaac +4 more
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Abstract Lipid nanoparticles (LNPs) have emerged as effective delivery vehicles for nucleic acids. However, conventional LNP formulations face several limitations, including poor endosomal escape and ApoE‐mediated liver tropism. Here, a novel class of LNPs, endogenous corticosteroid‐derived LNPs (cortico LNPs), is introduced in which ...
Ivan Isaac +4 more
openaire +1 more source
Fluorinated Lipid Nanoparticles for Enhancing mRNA Delivery Efficiency.
ACS NanoLipid nanoparticles (LNPs), a nonviral nucleic acid delivery system, have shown vast potential for vaccine development and disease treatment. LNPs assist mRNA to cross physiological barriers such as cell membranes and endosomes/lysosomes, promoting the ...
Huipeng Zhang +8 more
semanticscholar +1 more source
Systems and Control Transactions
The promising properties of lipid nanoparticles (LNPs) as drug carriers have been attracting significant attention in the field of drug delivery. However, further research is still required for a better understanding of their integration in the pharmaceutical industry.
Daniel V. Batista, Marco S. Reis
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The promising properties of lipid nanoparticles (LNPs) as drug carriers have been attracting significant attention in the field of drug delivery. However, further research is still required for a better understanding of their integration in the pharmaceutical industry.
Daniel V. Batista, Marco S. Reis
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Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2023
Xing-Jie Liang, Fangzhou Li
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Xing-Jie Liang, Fangzhou Li
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Structural characterization of mRNA lipid nanoparticles (LNPs) in the presence of mRNA-free LNPs
Journal of Controlled ReleaseXiaoxia Chen +8 more
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The mystery of membrane organization: composition, regulation and roles of lipid rafts
Nature Reviews Molecular Cell Biology, 2017Erdinc Sezgin +2 more
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