Results 101 to 110 of about 534,958 (311)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Clinical and biochemical compare of perimenopausal and menopausal women [PDF]

Al Ameen Journal of Medical Sciences
Background: Menopause is an integral part of female normal physiology as outcomes of most vital non-modifiable risk factor of aging with symptoms ranging from trivial to ominous.
Amrita Ghosh, Arghyadip Sahoo, Narendranath Hait, Brahmarshi Das   +3 more
doaj  

Seasonal Comparison of Lipid Composition and Metabolism in Parasitised and Non-Parasitised Clover Root Weevil (Sitona lepidus)

, 2014
Since its arrival in New Zealand the clover root weevil (Sitona lepidus (syn. flavescens) (Coleoptera: Curculionidae) (CRW) has caused serious damage to New Zealand’s agricultural sector. The introduction of the biocontrol agent, Microctonus aethiopoides
Brown, Jolene Mary
core  

The comparison of simvastatin and atorvastatin efficacy in lowering lipid profile and apolipoprotein-b of diabetic dyslipidemia patient [PDF]

, 2013
HMG-CoA reductase inhibitors (Statins) are effective lipid-lowering drugs for the treatment of dyslipidemia patients with type 2diabetes mellitus (T2DM).
Sony Wibisono, Budi Suprapti, Nur Palestin Ayumuyas, Debra Dorotea   +3 more
core  

Body measurements and lipid profile.

, 2016
Body measurements and lipid profile.
Marie-Claude Drolet (2742400), Micheline Noël (789003), Paul Isenring (214645), Rachelle Frenette-Cotton (788999), Andrée-Anne Marcoux (788998), Jacques Couet (2742403), Alexandre P. Garneau (761254), Richard Larivière (2742406)   +7 more
core   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

SERUM LIPID PROFILE

The Professional Medical Journal, 2018
… Objectives: This study was conducted to determine serum lipid profile in childrenof premature coronary heart disease patients and compare results between children havingparents with one, two or three risk factors. Study Design: A cross sectional comparative study.Patients and Methods: Ninety seven (97) subjects having parents with one risk factor ...
openaire   +2 more sources

LIPID PROFILE AND LIPID PEROXIDATION IN BRONCHIAL ASTHMA

, 2018
Background: Bronchial asthma, a chronic inflammatory condition, often triggered by allergy & oxidative stress, initiate lipid peroxidation& enhanced release of arachidonic acid from cell membrane.
Kamala Parhi, Behera PK, PK, Behera, Chatterjee, Gangadhar, Gangadhar Chatterjee, Parhi, Kamala Kanta   +5 more
core   +1 more source