Results 91 to 100 of about 919,034 (356)

Lipid Profile and Menopausal Status

open access: yesمجله كليه طب الكندي, 2008
Background: Dyslipidemia is a major cause of cardiovascular disease, which in turn, is the most common cause of female morbidity and mortality.
Fouad Hamad Al - Dahhan   +2 more
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Comparative analysis of serum lipid profile in adults with and without acne vulgaris in a tertiary care center in South India

open access: yesClinical Dermatology Review, 2020
Background: Acne is a chronic inflammatory disease of the pilosebaceous unit, affecting most teenagers during adolescence and at times may persist into adulthood also.
Halaguru Narayanaswamy Veena   +3 more
doaj   +1 more source

The free energy of biomembrane and nerve excitation and the role of anesthetics

open access: yes, 2018
In the electromechanical theory of nerve stimulation, the nerve impulse consists of a traveling region of solid membrane in a liquid environment. Therefore, the free energy necessary to stimulate a pulse is directly related to the free energy difference ...
Heimburg, Thomas   +3 more
core   +1 more source

Non-invasive depth profiling of the stratum corneum in vivo using confocal Raman microscopy considering the non-homogeneous distribution of keratin [PDF]

open access: yes, 2019
Confocal Raman microscopy has a number of advantages in investigating the human stratum corneum (SC) in vivo and ex vivo. The penetration profiles of xenobiotics in the SC, as well as depth profiles of the physiological parameters of the SC, such as the ...
Choe, Chun-Sik   +3 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Lipid profile changes after the acute COVID-19 period. Sub-analysis of the International Registry "Dynamics Analysis of Comorbidities in SARS-CoV-2 Survivors" (AKTIV SARS-CoV-2)" (12-month follow-up)

open access: yesРоссийский кардиологический журнал
Aim. To analyze the lipid profile changes during the acute phase of coronavirus disease 2019 (COVID-19) and within 12 months after discharge from the hospital (post-Covid period) in comparison with the lipid profile of patients before COVID-19.Material ...
G. P. Arutyunov   +27 more
doaj   +1 more source

Digging into Lipid Membrane Permeation for Cardiac Ion Channel Blocker d-Sotalol with All-Atom Simulations. [PDF]

open access: yes, 2018
Interactions of drug molecules with lipid membranes play crucial role in their accessibility of cellular targets and can be an important predictor of their therapeutic and safety profiles.
Bekker, Slava   +4 more
core  

Triiodothyronine and free thyroxine levels are differentially associated with metabolic profile and adiposity-related cardiovascular risk markers in euthyroid middle-aged subjects [PDF]

open access: yes, 2014
Background: We previously showed that in healthy young men a less favorable body composition is associated with higher FT3 levels within the euthyroid range.
De Buyzere, Marc   +6 more
core   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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