Results 71 to 80 of about 534,958 (311)

Effect of Tocotrienols on Lipid Profile in Rabbits

Journal of Rawalpindi Medical College, 2012
Background: To evaluate the effect of tocotrienols on serum lipids in cholesterol-fed rabbits. Methods: In this experimental study, thirty six, male New Zealand white rabbits were randomly allocated to three equal groups.
Uzma Shahid
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Novel lipid profiles and atherosclerotic cardiovascular disease risk: insights from a latent profile analysis

Lipids in Health and Disease
Background Dyslipidemia is a key contributor to atherosclerotic cardiovascular disease (ASCVD). Despite the well-established correlation between abnormal lipid metabolism and ASCVD, existing diagnostic and predictive models based on lipid indices alone ...
Hongli Wan, Haisheng Wu, Yuxi Wei, Simin Wang, Yuqiang Ji   +4 more
doaj   +1 more source

Lipid profile and alcoholism

International Journal of Advances in Medicine, 2019
Background: Alcoholism is a major threat to public health in both developed and developing countries. Alcohol has many effects on lipid profile, including inducing de novo fatty acid synthesis and inhibiting fatty acid oxidation in liver. Aim of this study was to study the effect of alcohol consumption on serum lipid profile in alcoholics and to ...
Sabin George, Sanju Daniel John, Salk George, Jasica Joy Thottiyil   +3 more
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

SERUM LIPID PROFILE;

The Professional Medical Journal, 2008
Objective: To determine the effects of Nigella sativa and sunflower oil diet intake on serum lipid profile in albino rats. Material& Methods: Eighty four albino rats with equal number of males and females were selected for the study, they were divided into six differentgroups, Control groups1,111,V,were given low fat diet(3%),high fat diet(20 ...
MUHAMMAD ANWAR BURIRO, MUHAMMAD TAYYAB
openaire   +2 more sources

L.)—studies of flesh lipid quality and metabolic profile

, 2016
The Baltic Sea is one of the world's most pollution-threatened brackish environments and limited direct consumption of fatty fish from the Baltic Sea is recommended. The use of decontaminated Baltic Sea fish raw materials as fish feed could be a strategy
Ali A. Moazzami, Ken Cheng, Sofia Trattner, Liane Wagner, Eva Brännäs, Moazzami, Ali,, Sveriges lantbruksuniversitet., Pedro Gómez‐Requeni, Schiller Vestergren, Anna,, Gómez Requeni, Pedro,, Brännäs, Eva,, Cheng, Ken,, Jana Pickova, Pickova, Jana,, Trattner, Sofia,, Wagner, Liane,, AnnaLotta Schiller Vestergren   +16 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Lipid Profile and Menopausal Status

مجله كليه طب الكندي, 2008
Background: Dyslipidemia is a major cause of cardiovascular disease, which in turn, is the most common cause of female morbidity and mortality.
Fouad Hamad Al - Dahhan, Lamia M. Al - Naama, *Ahlam Disher   +2 more
doaj