Results 131 to 140 of about 2,216,610 (312)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Effects of tumor necrosis factor-alpha inhibitors on lipid profiles in patients with psoriasis: a systematic review and meta-analysis

Frontiers in Immunology
BackgroundThere is no consensus on the effect of tumor necrosis factor-alpha (TNF-alpha) inhibitors on lipid profiles in patients with psoriasis. This study aimed to investigate the effects of TNF-alpha inhibitors on lipid profiles (triglycerides, total ...
Liang Su, Liang Su, Chunyan Xu, Hong Huang, Hong Huang, Peilian Zhang, Peilian Zhang, Jinrong Wang, Jinrong Wang, Xiaoyong Ouyang, Xiaoyong Ouyang, Xuesong Yang, Xuesong Yang, Jianzhou Ye, Jianzhou Ye   +14 more
doaj   +1 more source

lipid profiling

Citation: 'lipid profiling' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09843 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Manipulation of lipid rafts in neuronal cells [PDF]

, 2010
Lipid rafts are specialized plasma membrane micro-domains highly enriched in cholesterol, sphingolipids and glycosylphosphatidylinositol (GPI) anchored proteins.
Eckert, Gunter P.
core  

Lipid and glycaemic profiles after 10 weeks of training (mean ± SD).

, 2019
Lipid and glycaemic profiles after 10 weeks of training (mean ± SD).
Nathalie Boisseau (778574), Emilie Vazeille (349596), Pascal Sirvent (589813), Yolanda Fernandez Otero (6570023), Lydie Combaret (450737), Antoine Sourdrille (5338547), Richard Bonnet (241637), Florie Maillard (6570020), Vivien Chavanelle (778576), Geoffrey Delcros (6570026), Nicolas Barnich (277067), Pierre Sauvanet (209610)   +11 more
core   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Real-world glycemic control, exploratory cardiorenal indicators, and safety of polyethylene glycol loxenatide versus semaglutide in type 2 diabetes patients: a Chinese two-center retrospective cohort study

Frontiers in Endocrinology
ObjectiveTo compare the real-world efficacy and safety of high dose once-weekly glucagon-like peptide-1 receptor agonists polyethylene glycol loxenatide (PEG-Loxe) and subcutaneous (s.c.) semaglutide in patients with suboptimally controlled type 2 ...
Zelin Yu, Duoyi Fu, Jing Xu, Chujia Lin, Guoshu Yin, De Cai, Hongyan Jiang, Kai Ling, Jianqin Chen, Yeye Zhuo   +9 more
doaj   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Associations of lipid metabolite profiles with BMI and other metabolic traits.

, 2016
Associations of lipid metabolite profiles with BMI and other metabolic traits.
Ming-Huei Chen (73691), Martin G. Larson (110473), Susan Cheng (396864), Michelle Keyes (849366), Clary B. Clish (242594), Robert E. Gerszten (252468), Thomas J. Wang (252466), Eugene P. Rhee (849367), Ramachandran S. Vasan (110476), Jennifer E. Ho (849364), Anahita Ghorbani (849365)   +10 more
core   +1 more source