Results 61 to 70 of about 38,146 (252)
Frontiers in Plant Science, 2014 Plant cell-to-cell communication is mediated by nanopores called plasmodesmata (PDs) which are complex structures comprising plasma membrane (PM), highly packed endoplasmic reticulum and numerous membrane proteins.
Pamela Alejandra Naulin +2 more
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Advanced Science, EarlyView.Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He +9 more
wiley +1 more source
Advanced Science, EarlyView.Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh +22 more
wiley +1 more source
Association of active γ-secretase complex with lipid rafts
Journal of Lipid Research, 2005 Cholesterol has been implicated in the pathogenesis of Alzheimer's disease (AD). Although the underlying mechanisms are not yet clear, several studies have provided evidence for the involvement of cholesterol-rich lipid rafts in the production of amyloid
Yasuomi Urano +9 more
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Virus Infection and Lipid Rafts
Biological and Pharmaceutical Bulletin, 2006 Virus entry, assembly, and budding are important processes in the replication cycle of a virus. Viruses are dependent on host living cells for their replication. Viruses use the proliferative mechanism of host cells for replication of viral components.
Suzuki, Takashi, Suzuki, Yasuo
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Advanced Science, EarlyView.Organosilicon micelles enable background‐free molecular magnetic resonance imaging (MRI) while remaining fully compatible with standard proton (1H) hardware. By exploiting a spectrally silent 1H window at ∼0 ppm, the silicone nanotracer allows hotspot detection by 1H chemical‐shift imaging (CSI) without metals or heteronuclei, enabling direct overlay ...
Martin Orsagh +4 more
wiley +1 more source
Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants
Advanced Science, EarlyView.Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer +17 more
wiley +1 more source
Interplay Between Membrane Adhesion and Distribution of Lipid Rafts
SurfacesAdhesion of cell membranes is relevant to many biological processes and arises from the specific binding of membrane-anchored receptor proteins to their ligands present in the apposing membrane.
Iyad Bin Hussain Thalakodan +1 more
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Coalescence of RAGE in Lipid Rafts in Response to Cytolethal Distending Toxin-Induced Inflammation
Frontiers in Immunology, 2019 The receptor for advanced glycation end products (RAGE) interacts with various molecules in the cell membrane to induce an inflammatory response. The cytolethal distending toxin (CDT) produced by Campylobacter jejuni contains three subunits: CdtA, CdtB ...
Hwai-Jeng Lin +19 more
doaj +1 more source
Of Rafts and Lipid Chain Lengths [PDF]
Biophysical Journal, 2015 Plasma membranes are believed to be highly heterogeneous, and to contain coexisting liquid-ordered domains (known as rafts), which are enriched in cholesterol and sphingomyelin, and liquid-disordered domains. Similar heterogeneities exist in synthetic membrane systems. Previous studies of asymmetric lipid bilayers have demonstrated that the presence of
Hristova, Kalina, Hinderliter, Anne
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