Results 1 to 10 of about 981 (113)

Primary cilia and lipid raft dynamics

open access: yesOpen Biology, 2021
Primary cilia, antenna-like structures of the plasma membrane, detect various extracellular cues and transduce signals into the cell to regulate a wide range of functions.
Yuhei Nishimura, Takashi Shiromizu
exaly   +3 more sources

Lipid Raft, Regulator of Plasmodesmal Callose Homeostasis

open access: yesPlants, 2017
: The specialized plasma membrane microdomains known as lipid rafts are enriched by sterols and sphingolipids. Lipid rafts facilitate cellular signal transduction by controlling the assembly of signaling molecules and membrane protein trafficking ...
Jae-Yean Kim, Arya Bagus Boedi Iswanto
exaly   +3 more sources

α1-nAchR-Mediated Signaling Through Lipid Raft Is Required for Nicotine-Induced NLRP3 Inflammasome Activation and Nicotine-Accelerated Atherosclerosis

open access: yesFrontiers in Cell and Developmental Biology, 2021
BackgroundNicotine exerts direct effects on multiple cell types in the cardiovascular system by associating with its high-affinity nicotinic acetylcholine receptors (nAchRs).
Fengqi Duan   +8 more
doaj   +1 more source

Cold induces micro- and nano-scale reorganization of lipid raft markers at mounds of T-cell membrane fluctuations. [PDF]

open access: yesPLoS ONE, 2009
Whether and how cold causes changes in cell-membrane or lipid rafts remain poorly characterized. Using the NSOM/QD and confocal imaging systems, we found that cold caused microscale redistribution of lipid raft markers, GM1 for lipid and CD59 for protein,
Yong Chen   +3 more
doaj   +1 more source

Interaction of drugs with lipid raft membrane domains as a possible target

open access: yesDrug Target Insights, 2020
Introduction: Plasma membranes are not the homogeneous bilayers of uniformly distributed lipids but the lipid complex with laterally separated lipid raft membrane domains, which provide receptor, ion channel and enzyme proteins with a platform.
Hironori Tsuchiya, Maki Mizogami
doaj   +1 more source

Lipid Rafts and Pseudotyping [PDF]

open access: yesJournal of Virology, 2001
ABSTRACTSpecific interactions between envelope and core proteins govern the membrane assembly of most enveloped viruses. Despite this, mixed infections lead to pseudotyping, the association of the viral cores of one virus with the envelopes of another. How does this occur?
W F, Pickl   +2 more
openaire   +2 more sources

Role of membrane microdomains in compartmentation of cAMP signaling. [PDF]

open access: yesPLoS ONE, 2014
Spatially restricting cAMP production to discrete subcellular locations permits selective regulation of specific functional responses. But exactly where and how cAMP signaling is confined is not fully understood.
Shailesh R Agarwal   +7 more
doaj   +1 more source

HHcy Induces Pyroptosis and Atherosclerosis via the Lipid Raft-Mediated NOX-ROS-NLRP3 Inflammasome Pathway in apoE−/− Mice

open access: yesCells, 2022
Lipid rafts play important roles in signal transduction, particularly in responses to inflammatory processes. The current study aimed to identify whether lipid raft-mediated inflammation contributes to hyperhomocysteinemia (HHcy)-accelerated ...
Sijun Liu   +4 more
doaj   +1 more source

Structure of Cholesterol in Lipid Rafts [PDF]

open access: yesPhysical Review Letters, 2014
Rafts, or functional domains, are transient nano- or mesoscopic structures in the plasma membrane and are thought to be essential for many cellular processes such as signal transduction, adhesion, trafficking and lipid/protein sorting. Observations of these membrane heterogeneities have proven challenging, as they are thought to be both small and short-
Toppozini, Laura   +6 more
openaire   +3 more sources

Generation of stable lipid raft microdomains in the enterocyte brush border by selective endocytic removal of non-raft membrane. [PDF]

open access: yesPLoS ONE, 2013
The small intestinal brush border has an unusually high proportion of glycolipids which promote the formation of lipid raft microdomains, stabilized by various cross-linking lectins. This unique membrane organization acts to provide physical and chemical
E Michael Danielsen, Gert H Hansen
doaj   +1 more source

Home - About - Disclaimer - Privacy