Results 1 to 10 of about 37,326 (154)
Lipid rafts as a therapeutic target
Journal of Lipid Research, 2020 Lipid rafts regulate the initiation of cellular metabolic and signaling pathways by organizing the pathway components in ordered microdomains on the cell surface.
Dmitri Sviridov +2 more
doaj +3 more sources
Targeting the ARF6-dependent recycling pathway to alter lipid rafts and reduce inflammation [PDF]
Journal of Lipid ResearchPartitioning of inflammatory receptors into lipid rafts is essential for their function making lipid rafts a promising target for anti-inflammatory therapies.
Nigora Mukhamedova +12 more
doaj +2 more sources
Lipid Rafts: The Maestros of Normal Brain Development [PDF]
BiomoleculesLipid rafts, specialised microdomains within cell membranes, play a central role in orchestrating various aspects of neurodevelopment, ranging from neural differentiation to the formation of functional neuronal networks.
Barbara Viljetić +6 more
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Lipid rafts, cholesterol, and the brain [PDF]
Neuropharmacology, 2008 Lipid rafts are specialized membrane microdomains that serve as organizing centers for assembly of signaling molecules, influence membrane fluidity and trafficking of membrane proteins, and regulate different cellular processes such as neurotransmission and receptor trafficking.
Anne Kenworthy, Željka Korade
exaly +3 more sources
Lipid Rafts and Plant Gravisensitivity. [PDF]
Life (Basel), 2022 The necessity to include plants as a component of a Bioregenerative Life Support System leads to investigations to optimize plant growth facilities as well as a better understanding of the plant cell membrane and its numerous activities in the signaling, transport, and sensing of gravity, drought, and other stressors.
Kordyum EL, Artemenko OA, Hasenstein KH.
europepmc +4 more sources
Structural and functional modifications of neuronal lipid rafts: implications for HIV-associated neurological disorders [PDF]
Journal of NeuroinflammationBackground HIV-associated neurological disorders (HAND) remain a prevalent co-morbidity of HIV infection. Growing evidence implicates the HIV protein Nef in this process, as Nef increases the abundance of neuronal lipid rafts - cholesterol- and ...
Ying Fu +14 more
doaj +2 more sources
Lipid rafts, caveolae, and epidermal growth factor receptor family: friends or foes? [PDF]
Cell Communication and SignalingLipid rafts are dynamic microdomains enriched with cholesterol and sphingolipids that play critical roles in cellular processes by organizing and concentrating specific proteins involved in signal transduction.
Francesca Ruzzi +9 more
doaj +2 more sources
Methodological Pitfalls of Investigating Lipid Rafts in the Brain: What Are We Still Missing? [PDF]
BiomoleculesThe purpose of this review is to succinctly examine the methodologies used in lipid raft research in the brain and to highlight the drawbacks of some investigative approaches.
Kristina Mlinac-Jerkovic +3 more
doaj +2 more sources
Imaging lipid rafts reveals the principle of ApoE4-induced Aβ upregulation in human neurons [PDF]
iScienceSummary: Lipid rafts in plasma membranes are thought to provide a platform for regulating signaling pathways by increasing the expression or proximity of proteins in the same pathway.
Se-In Lee +7 more
doaj +2 more sources
Lipid Rafts and Pseudotyping [PDF]
Journal of Virology, 2001 ABSTRACTSpecific interactions between envelope and core proteins govern the membrane assembly of most enveloped viruses. Despite this, mixed infections lead to pseudotyping, the association of the viral cores of one virus with the envelopes of another. How does this occur?
W F, Pickl +2 more
openaire +2 more sources