Results 11 to 20 of about 38,146 (252)
Isolation of Lipid Rafts from Cultured Mammalian Cells and Their Lipidomics Analysis
Bio-Protocol, 2020 Lipid rafts are distinct liquid-ordered domains of plasma membranes of most eukaryotic cells providing platform for signaling pathways. Lipid composition of rafts is critical for their structural integrity and for regulation of signaling pathways ...
Nigora Mukhamedova +4 more
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Structure of Cholesterol in Lipid Rafts [PDF]
Physical Review Letters, 2014 Rafts, or functional domains, are transient nano- or mesoscopic structures in the plasma membrane and are thought to be essential for many cellular processes such as signal transduction, adhesion, trafficking and lipid/protein sorting. Observations of these membrane heterogeneities have proven challenging, as they are thought to be both small and short-
Toppozini, Laura +6 more
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Protective Function of Lipid Rafts [PDF]
Caspian Journal of Environmental Sciences, 2021 The study of lipid rafts allowed us to take a new look at the morphology, organization and functioning of membranes, both of animal and plant origin.
I.S. Kapustina +4 more
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Journal of Lipid Research, 2020 Lipid rafts are small, dynamic membrane areas characterized by the clustering of selected membrane lipids as the result of the spontaneous separation of glycolipids, sphingolipids, and cholesterol in a liquid-ordered phase.
Sara Grassi +5 more
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The lipid rafts in cancer stem cell: a target to eradicate cancer
Stem Cell Research & Therapy, 2022 Cancer stem cells (CSCs) are a subpopulation of cancer cells with stem cell properties that sustain cancers, which may be responsible for cancer metastasis or recurrence.
Shuo Zhang +6 more
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Lipid rafts and pathogens: the art of deception and exploitation
Journal of Lipid Research, 2020 Lipid rafts, solid regions of the plasma membrane enriched in cholesterol and glycosphingolipids, are essential parts of a cell. Functionally, lipid rafts present a platform that facilitates interaction of cells with the outside world.
Michael I. Bukrinsky +2 more
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Planta, 2005 About two decades ago a provocative hypothesis evolved suggesting that the plasma membrane (PM) of mammalian and probably other eukaryotic cells constitutes a mosaic of patches comprising particular molecular compositions. These scattered lipid bilayer microdomains are supposedly enriched in sterols as well as sphingolipids and depleted in unsaturated ...
Bhat, R., Panstruga, R.
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Aggregation of lipid rafts activates c-met and c-Src in non-small cell lung cancer cells
BMC Cancer, 2018 Background Activation of c-Met, a receptor tyrosine kinase, induces radiation therapy resistance in non-small cell lung cancer (NSCLC). The activated residual of c-Met is located in lipid rafts (Duhon et al. Mol Carcinog 49:739-49, 2010).
Juan Zeng +6 more
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Synaptic membrane rafts: traffic lights for local neurotrophin signalling?
Frontiers in Synaptic Neuroscience, 2013 Lipid rafts, cholesterol and lipid rich microdomains, are believed to play important roles as platforms for the partitioning of transmembrane and synaptic proteins involved in synaptic signalling, plasticity and maintenance.
Barbara eZonta, Liliana eMinichiello
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Plant Physiology, 2007 Current thinking on lipid membrane organization has evolved from the seminal fluid mosaic model proposed by [Singer and Nicolson (1972)][1]. Subsequent studies on plasma membranes suggest that biological membranes are not a simple homogeneous layer of proteins and lipids, but rather are ...
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