Results 21 to 30 of about 38,146 (252)

The ins and outs of lipid rafts: functions in intracellular cholesterol homeostasis, microparticles, and cell membranes

Journal of Lipid Research, 2020
Cellular membranes are not homogenous mixtures of proteins; rather, they are segregated into microdomains on the basis of preferential association between specific lipids and proteins. These microdomains, called lipid rafts, are well known for their role
Amber B. Ouweneel, Michael J. Thomas, Mary G. Sorci-Thomas   +2 more
doaj   +1 more source

Selective Association of Outer Surface Lipoproteins with the Lipid Rafts of Borrelia burgdorferi

mBio, 2014
Borrelia burgdorferi contains unique cholesterol-glycolipid-rich lipid rafts that are associated with lipoproteins. These complexes suggest the existence of macromolecular structures that have not been reported for prokaryotes. Outer surface lipoproteins
Alvaro Toledo, Jameson T. Crowley, James L. Coleman, Timothy J. LaRocca, Salvatore Chiantia, Erwin London, Jorge L. Benach   +6 more
doaj   +1 more source

Role of Lipid Rafts in Pathogen-Host Interaction - A Mini Review

Frontiers in Immunology, 2022
Lipid rafts, also known as microdomains, are important components of cell membranes and are enriched in cholesterol, glycophospholipids and receptors.
Rakesh Kulkarni, Rakesh Kulkarni, Erik A. C. Wiemer, Wen Chang   +3 more
doaj   +1 more source

Lipid rafts: bringing order to chaos

Journal of Lipid Research, 2003
Lipid rafts are subdomains of the plasma membrane that contain high concentrations of cholesterol and glycosphingolipids. They exist as distinct liquid-ordered regions of the membrane that are resistant to extraction with nonionic detergents.
Linda J. Pike
doaj   +1 more source

Increased lipid rafts and accelerated lipopolysaccharide-induced tumor necrosis factor-α secretion in Abca1-deficient macrophagess⃞

Journal of Lipid Research, 2007
Lipid rafts on the cell surface are believed to be very important as platforms for various cellular functions. The aim of this study was to know whether defective lipid efflux may influence lipid rafts on the cell surface and their related cellular ...
Masahiro Koseki, Ken-ichi Hirano, Daisaku Masuda, Chiaki Ikegami, Masaki Tanaka, Akemi Ota, Jose C. Sandoval, Yumiko Nakagawa-Toyama, Satoshi B. Sato, Toshihide Kobayashi, Yukiko Shimada, Yoshiko Ohno-Iwashita, Fumihiko Matsuura, Iichiro Shimomura, Shizuya Yamashita   +14 more
doaj   +1 more source

Biology of Lipid Rafts: Introduction to the Thematic Review Series

Journal of Lipid Research, 2020
Lipid rafts are organized plasma membrane microdomains, which provide a distinct level of regulation of cellular metabolism and response to extracellular stimuli, affecting a diverse range of physiologic and pathologic processes.
Dmitri Sviridov, Yury I. Miller
doaj   +1 more source

The Important Role of Lipid Raft-Mediated Attachment in the Infection of Cultured Cells by Coronavirus Infectious Bronchitis Virus Beaudette Strain. [PDF]

PLoS ONE, 2017
Lipid raft is an important element for the cellular entry of some viruses, including coronavirus infectious bronchitis virus (IBV). However, the exact role of lipid rafts in the cellular membrane during the entry of IBV into host cells is still unknown ...
Huichen Guo, Mei Huang, Quan Yuan, Yanquan Wei, Yuan Gao, Lejiao Mao, Lingjun Gu, Yong Wah Tan, Yanxin Zhong, Dingxiang Liu, Shiqi Sun   +10 more
doaj   +1 more source

10-Gingerol Targets Lipid Rafts Associated PI3K/Akt Signaling in Radio-Resistant Triple Negative Breast Cancer Cells

Molecules, 2020
10-Gingerol is a major phenolic lipid found in the rhizomes of ginger (Zingiber officinale). Being amphiphilic in nature, phenolic lipids have the ability to incorporate into cell membranes and modulate membrane properties.
Meran Keshawa Ediriweera, Jeong Yong Moon, Yen Thi-Kim Nguyen, Somi Kim Cho   +3 more
doaj   +1 more source

Hematopoiesis is regulated by cholesterol efflux pathways and lipid rafts: connections with cardiovascular diseases

Journal of Lipid Research, 2020
Lipid rafts are highly ordered regions of the plasma membrane that are enriched in cholesterol and sphingolipids and play important roles in many cells.
Pooranee K. Morgan, Longhou Fang, Graeme I. Lancaster, Andrew J. Murphy   +3 more
doaj   +1 more source

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

Hepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol, Antoine Rimbert, Justina C. Wolters, Marieke Smit, Vincent W. Bloks, Niels J. Kloosterhuis, Nicolette C. A. Huijkman, Mirjam H. Koster, Umesh Tharehalli, Simon M. de Neck, Colin Bournez, Marceline M. Fuh, Jeroen Kuipers, Sujith Rajan, Alain de Bruin, Henry N. Ginsberg, Gerard J. P. van Westen, M. Mahmood Hussain, Ludger Scheja, Joerg Heeren, Philip Zimmerman, Bart van de Sluis, Jan Albert Kuivenhoven   +22 more
wiley   +1 more source