Results 11 to 20 of about 34,012 (255)

Lipid Rafts and Pseudotyping [PDF]

open access: yesJournal of Virology, 2001
ABSTRACTSpecific interactions between envelope and core proteins govern the membrane assembly of most enveloped viruses. Despite this, mixed infections lead to pseudotyping, the association of the viral cores of one virus with the envelopes of another. How does this occur?
W F, Pickl   +2 more
openaire   +2 more sources

Structure of Cholesterol in Lipid Rafts [PDF]

open access: yesPhysical Review Letters, 2014
Rafts, or functional domains, are transient nano- or mesoscopic structures in the plasma membrane and are thought to be essential for many cellular processes such as signal transduction, adhesion, trafficking and lipid/protein sorting. Observations of these membrane heterogeneities have proven challenging, as they are thought to be both small and short-
Toppozini, Laura   +6 more
openaire   +3 more sources

HHcy Induces Pyroptosis and Atherosclerosis via the Lipid Raft-Mediated NOX-ROS-NLRP3 Inflammasome Pathway in apoE−/− Mice

open access: yesCells, 2022
Lipid rafts play important roles in signal transduction, particularly in responses to inflammatory processes. The current study aimed to identify whether lipid raft-mediated inflammation contributes to hyperhomocysteinemia (HHcy)-accelerated ...
Sijun Liu   +4 more
doaj   +1 more source

Generation of stable lipid raft microdomains in the enterocyte brush border by selective endocytic removal of non-raft membrane. [PDF]

open access: yesPLoS ONE, 2013
The small intestinal brush border has an unusually high proportion of glycolipids which promote the formation of lipid raft microdomains, stabilized by various cross-linking lectins. This unique membrane organization acts to provide physical and chemical
E Michael Danielsen, Gert H Hansen
doaj   +1 more source

Comprehensive bioinformatic analyses of KRAS mutations and deciphering chromatin modification landscape of Caveolin-1 gene by lipid raft destabilization induced modulation of RAS-MAPK axis in colon cancer

open access: yesAdvances in Cancer Biology - Metastasis, 2022
Ras signaling contributes to multiple components of cellular functions. To gain insight into the role of KRAS mutant isoforms, we bioinformatically analyzed and noticed that KRAS mutations at G12V, G12D, and G13D positions are prominent in colorectal ...
Ankan Roy   +5 more
doaj   +1 more source

Lipid rafts in plants

open access: yesPlanta, 2005
About two decades ago a provocative hypothesis evolved suggesting that the plasma membrane (PM) of mammalian and probably other eukaryotic cells constitutes a mosaic of patches comprising particular molecular compositions. These scattered lipid bilayer microdomains are supposedly enriched in sterols as well as sphingolipids and depleted in unsaturated ...
Bhat, R., Panstruga, R.
openaire   +3 more sources

UL11 Protein Is a Key Participant of the Duck Plague Virus in Its Life Cycle

open access: yesFrontiers in Microbiology, 2022
Tegument protein UL11 plays a critical role in the life cycle of herpesviruses. The UL11 protein of herpesviruses is important for viral particle entry, release, assembly, and secondary envelopment.
Linjiang Yang   +54 more
doaj   +1 more source

Lipid Rafts in Plants [PDF]

open access: yesPlant Physiology, 2007
Current thinking on lipid membrane organization has evolved from the seminal fluid mosaic model proposed by [Singer and Nicolson (1972)][1]. Subsequent studies on plasma membranes suggest that biological membranes are not a simple homogeneous layer of proteins and lipids, but rather are ...
openaire   +2 more sources

Sesquiterpene Alcohol Cedrol Chemosensitizes Human Cancer Cells and Suppresses Cell Proliferation by Destabilizing Plasma Membrane Lipid Rafts

open access: yesFrontiers in Cell and Developmental Biology, 2021
Chemosensitization of cancer cells with small molecules may improve the therapeutic index of antitumoral agents by making tumor cells sensitive to the drug regimen and thus overcome the treatment resistance and side effects of single therapy.
Siddhartha Kumar Mishra   +7 more
doaj   +1 more source

The Lipid Raft Proteome of African Trypanosomes Contains Many Flagellar Proteins

open access: yesPathogens, 2017
Lipid rafts are liquid-ordered membrane microdomains that form by preferential association of 3-β-hydroxysterols, sphingolipids and raft-associated proteins often having acyl modifications.
Aabha I. Sharma   +2 more
doaj   +1 more source

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