Results 61 to 70 of about 4,282,587 (298)

Three phosphatidylcholines as a potential early-diagnostic signature for hyperglycemia in preschool-aged children: a cross-sectional pilot study

Frontiers in Endocrinology
ObjectiveAlthough lipid metabolism dysregulation commonly accompanies elevated blood glucose, lipidomic studies in hyperglycemic children remain limited.
Haifeng Zhang, Jing Wang, Yueguang Lv, Yiying Huang, Yuanyuan Guo, Chang Jiang, Ting Zhang, Gongshu Liu, Fangfang Chen   +8 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

GATA-type transcriptional factor SpGAT1 interacts with SpMIG1 and promotes lipid accumulation in the oleaginous yeast $$Saitozyma \ podzolica$$ S a i t o z y m a p o d z o l i c a zwy-2-3

Biotechnology for Biofuels and Bioproducts, 2022
Background In oleaginous yeast, nitrogen limitation is a critical parameter for lipid synthesis. GATA-family transcriptional factor GAT1, a member of the target of rapamycin (TOR) pathway and nitrogen catabolite repression (NCR), regulates nitrogen ...
Yulu Ran, Hui Xu, Qingzhuoma Yang, Yi Xu, Huahao Yang, Dairong Qiao, Yi Cao   +6 more
doaj   +1 more source

Lipid Ratios for Diagnosis and Prognosis of Pulmonary Hypertension

American Journal of Respiratory and Critical Care Medicine
Abstract Rationale Pulmonary hypertension (PH) poses a significant health threat. Current biomarkers for PH lack specificity and have poor prognostic capabilities. Objectives To develop better biomarkers for PH that ...
Natalie Bordag, Bence Miklos Nagy, Elmar Zügner, Helga Ludwig, Vasile Foris, Chandran Nagaraj, Valentina Biasin, Gabor Kovacs, Nikolaus Kneidinger, Ulrich Bodenhofer, Christoph Magnes, Bradley A. Maron, Silvia Ulrich, Tobias J. Lange, Thomas O. Eichmann, Konrad Hoetzenecker, Thomas Pieber, Horst Olschewski, Andrea Olschewski   +18 more
openaire   +2 more sources

Lipid bilayer composition influences small multidrug transporters [PDF]

, 2008
Background: Membrane proteins are influenced by their surrounding lipids. We investigate the effect of bilayer composition on the membrane transport activity of two members of the small multidrug resistance family; the Escherichia coli transporter, EmrE
Charalambous, K, Curnow, Paul, Curnow, P., Curnow, P, Miller, D, Charalambous, Kalypso, Booth, Paula J, Miller, D., Booth, P.J., Miller, David, Booth, PJ, David Miller, Paula J Booth, Kalypso Charalambous, Paul Curnow   +14 more
core   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and telomere length: the NHANES 1999–2002

Frontiers in Cardiovascular Medicine
BackgroundThe relationship between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and telomere length (TL) remains unclear.
Mingjie Liu, Chendong Wang, Bai Wei
doaj   +1 more source

Minimizing the ratio of ionizable lipid in lipid nanoparticles for in vivo base editing

National Science Review
ABSTRACT Lipid nanoparticles (LNPs) have gained clinical approval as carriers for both siRNA and mRNA. Among the crucial components of LNPs, ionizable lipids play a pivotal role in determining the efficiency of RNA delivery. In this study, we synthesized a series of ionizable lipids, denoted as HTO, with a higher count of hydroxyl groups
Qiubing Chen, Xuebin Wang, Yizhou Zhang, Ming Tian, Junyi Duan, Ying Zhang, Hao Yin   +6 more
openaire   +2 more sources

Contribution of trifluoperazine/lipid ratio and drug ionization to hemolysis

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1998
The interaction of the antipsychotic drug trifluoperazine (TFP) with membranes was investigated in terms of lipid phase perturbation. TFP partition coefficients (P) were measured by phase separation between octanol/water and model membranes/water. The profile of P values at pH 7.4 was: microsomes (7172+/-1229)>liposomes (1916+/-341)>erythrocyte ghosts (
Valéria Pinheiro Malheiros, Sônia, de Paula, Eneida, Correa Meirelles, Nilce   +2 more
openaire   +2 more sources

The demonstration of the invariant lipid-free composition and the mechanism varying energy and the main components of some mammal meats consisting of muscle and adipose tissue [PDF]

, 2009
Background: The assumption of an invariant fat-free or lipid-free composition is prerequisite for most methods of the estimation of body composition in mammals including human but has not been theoretically demonstrated. Objective: To ...
Mitsugu Inoue, Kazuyo Tsugita
core   +1 more source