Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth +8 more
wiley +1 more source
[Lipid rescue as a bail-out strategy in a repeatedly resuscitated patient]. [PDF]
Ackmann J +4 more
europepmc +1 more source
[Fungal infections of skin and nails]. [PDF]
Nenoff P, Mayser P, Uhrlaß S.
europepmc +1 more source
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
Human papillomavirus-encoded microRNAs: key regulators in cervical cancer development. [PDF]
Bencheikh S +6 more
europepmc +1 more source
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han +8 more
wiley +1 more source
Silent Spread of <i>Borrelia</i> Infection in Sardinia, Italy: Implications for Integrated Surveillance in the Mediterranean. [PDF]
Arghittu A +10 more
europepmc +1 more source
[Safety aspects during treatment with clozapine. : Monitoring and rechallenge - a narrative review]. [PDF]
Berger SJ, Hofer A.
europepmc +1 more source
A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Bonn: Univ.-Prof. Dr. Dr. Eva Schulte leitet neue Sektion für Psychiatrische Genomik. [PDF]
Schulte E.
europepmc +1 more source

