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Changes to the membrane proteins and rearrangement of the cytoskeleton must occur for a reticulocyte to mature into a red blood cell (RBC). Different mechanisms of reticulocyte maturation have been proposed to reduce the size and volume of the reticulocyte plasma membrane and to eliminate residual organelles.
Stevens-Hernandez, Christian J. +1 more
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Objective: To explore the effect of pomalidomide on the maturation of monocyte-derived dendritic cells (moDCs) from healthy donors (HDs) and multiple myeloma (MM) patients.Methods: MoDCs were generated by the incubation of monocytes from peripheral blood
Xi Wang +7 more
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Validating expression of beta cell maturation-associated genes in human pancreas development
The identification of genes associated with human pancreatic beta cell maturation could stimulate a better understanding of normal human islet development and function, be informative for improving stem cell-derived islet (SC-islet) differentiation, and ...
Daniel M. Tremmel +7 more
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Inflammatory-driven NK cell maturation and its impact on pathology
NK cells are innate lymphocytes involved in a large variety of contexts and are crucial in the immunity to intracellular pathogens as well as cancer due to their ability to kill infected or malignant cells.
Elsa Bourayou, Rachel Golub
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Arteriovenous fistula (AVF) is vascular access created for hemodialysis in end-stage renal disease patients. AVF creation causes increased blood flow in the outflow vein with increased pressure. Increased blood flow, blood volume, and shear stress causes
Vikrant Rai, Devendra K. Agrawal
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Silica nanoparticles (SiNPs) are generally regarded as safe and may represent an attractive carrier platform for nanomedical applications when loaded with biopharmaceuticals. Surface functionalization by different chemistries may help to optimize protein
Benjamin Punz +6 more
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An Overview of the Occurrence of Bioactive Peptides in Different Types of Cheeses
The search for improvements in quality of life has increasingly involved changes in the diet, especially the consumption of foods which, in addition to having good nutritional value, are characterized by offering health benefits. Among the molecules that
Adriano Henrique do Nascimento Rangel +9 more
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Towards a typology of continuative expressions
This paper investigates the cross-linguistic diversity of continuative (‘still’) expressions. Based on a genealogically stratified sample of 120 languages, the continuative expressions are systematically analyzed according to the four following ...
Anastasia Panova
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Use of Specific Chemical Reagents for Detection of Modified Nucleotides in RNA
Naturally occurring cellular RNAs contain an impressive number of chemically distinct modified residues which appear posttranscriptionally, as a result of specific action of the corresponding RNA modification enzymes.
Isabelle Behm-Ansmant +2 more
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Chlamydia trachomatis usually causes mucosal infections, bringing considerable morbidity and socioeconomic burden worldwide. We previously revealed that IL-27/IL-27R mediates protection against chlamydial invasion by promoting a protective Th1 response ...
Jiajia Zeng +9 more
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