Results 21 to 30 of about 715,291 (268)

IL-27 Signaling Promotes Th1 Response by Downregulating IL-10 Production in DCs during Chlamydial Respiratory Infection

open access: yesMicroorganisms, 2023
Chlamydia trachomatis usually causes mucosal infections, bringing considerable morbidity and socioeconomic burden worldwide. We previously revealed that IL-27/IL-27R mediates protection against chlamydial invasion by promoting a protective Th1 response ...
Jiajia Zeng   +9 more
doaj   +1 more source

Maturity and maturity models in lean construction

open access: yesConstruction Economics and Building, 2014
In recent years there has been an increasing interest in maturity models in management-related disciplines; which reflects a growing recognition that becoming more mature and having a model to guide the route to maturity can help organisations in managing major transformational change.
Nesensohn, Claus   +3 more
openaire   +5 more sources

Exceptional increase in the creep life of magnesium rare-earth alloys due to localized bond stiffening

open access: yesNature Communications, 2017
Adding very small amounts of zinc to magnesium alloys containing rare earth elements dramatically improves their creep life. Here, the authors use first principles calculations and atomic-scale characterization to show that this is due to stiff covalent ...
Deep Choudhuri   +6 more
doaj   +1 more source

In Vitro Maturation of Oocytes in Women at Risk of Ovarian Hyperstimulation Syndrome-A Prospective Multicenter Cohort Study [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2019
Background: In vitro maturation (IVM) is an artificial reproductive technology in which immature oocytes are harvested from the ovaries and subsequently will be matured in vitro.
Sanne C. Braam   +8 more
doaj   +1 more source

Maturation of Aluminium Adsorbed Antigens Contributes to the Creation of Homogeneous Vaccine Formulations

open access: yesVaccines, 2023
Although aluminium-based vaccines have been used for almost over a century, their mechanism of action remains unclear. It is established that antigen adsorption to the adjuvant facilitates delivery of the antigen to immune cells at the injection site. To
Donatello Laera   +7 more
doaj   +1 more source

IGF-I Medium Supplementation Improves Singly Cultured Cat Oocyte Maturation and Embryo Development In Vitro

open access: yesAnimals, 2021
Embryo production is a routine procedure in several species. However, in felids, the effectiveness of this approach is far behind that in the majority of laboratory species.
Lorena Fernandez-Gonzalez   +5 more
doaj   +1 more source

The C-Terminal Domain of RNase H and the C-Terminus Amino Acid Residue Regulate Virus Release and Autoprocessing of a Defective HIV-1 Possessing M50I and V151I Changes in Integrase

open access: yesViruses, 2022
Previously, we reported that an HIV-1 variant containing Met-to-Ile change at codon 50 and Val-to-Ile mutation at codon 151 of integrase (IN), HIV(IN:M50I/V151I), was an impaired virus.
Tomozumi Imamichi   +4 more
doaj   +1 more source

Role of Drug Transporters in Elucidating Inter-Individual Variability in Pediatric Chemotherapy-Related Toxicities and Response

open access: yesPharmaceuticals, 2022
Pediatric cancer treatment has evolved significantly in recent decades. The implementation of risk stratification strategies and the selection of evidence-based chemotherapy combinations have improved survival outcomes.
Ashwin Kamath   +5 more
doaj   +1 more source

Changes in age and maturity of anadromous whitefish (Coregonus lavaretus) in the northern Baltic Sea from 1998 to 2014

open access: yesAquatic Living Resources, 2021
The maturation of anadromous whitefish (Coregonus lavaretus) was analysed from samples taken from commercial coastal fishing in 1998–2014 in the Gulf of Bothnia. Whitefish matured at a younger age from year to year.
Veneranta Lari   +3 more
doaj   +1 more source

Influence of photon, proton and carbon ion irradiation on differentiation, maturation and functionality of dendritic cells

open access: yesFrontiers in Bioscience-Scholar, 2022
While the primary purpose of radiotherapy (RT) is the elimination of cancer cells by inducing DNA-damage, considerable evidence emerges that anti-neoplastic effects extend beyond mere tumor cell killing. These secondary effects are based on activation of
Laila König   +7 more
doaj   +1 more source

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