Results 21 to 30 of about 895,186 (317)

Heterozygous premature termination in zinc-finger domain of Krüppel-like factor 2 gene associates with dysregulated immunity

Frontiers in Immunology, 2022
Krüppel-like factor 2 (KLF2) is a transcription factor with significant roles in development, maturation, differentiation, and proliferation of several cell types.
Nora Pernaa, Salla Keskitalo, Iftekhar Chowdhury, Antti Nissinen, Virpi Glumoff, Riikka Keski-Filppula, Riikka Keski-Filppula, Riikka Keski-Filppula, Juhani Junttila, Kari K. Eklund, Wenny Santaniemi, Sanna Siitonen, Mikko RJ. Seppänen, Paula Vähäsalo, Paula Vähäsalo, Paula Vähäsalo, Markku Varjosalo, Pirjo Åström, Timo Hautala   +18 more
doaj   +1 more source

Protease mediated maturation of HIV: Inhibitors of protease and the maturation process [PDF]

, 2012
Protease-mediated maturation of HIV-1 virus particles is essential for virus infectivity. Maturation occurs concomitant with immature virus particle release and is mediated by the viral protease (PR), which sequentially cleaves the Gag and Gag-Pol ...
Catherine S. Adamson, Adamson, Catherine S   +1 more
core   +1 more source

Vaccinia Virus Infection Requires Maturation of Macropinosomes. [PDF]

, 2015
The prototypic poxvirus, vaccinia virus (VACV), occurs in two infectious forms, mature virions (MVs) and extracellular virions (EVs). Both enter HeLa cells by inducing macropinocytic uptake.
Mercer, Jason, Rizopoulos, Zaira, Balistreri, G, Kilcher, S, Mercer, J, Syedbasha, M, Kilcher, Samuel, Helenius, Ari, Balistreri, Giuseppe, Rizopoulos, Z, Syedbasha, Mohammedyaseen, Martin, Caroline K., Martin, CK, Helenius, A   +13 more
core   +1 more source

Considering maturation status and relative age in the longitudinal evaluation of junior rugby league players. [PDF]

, 2013
This study longitudinally evaluated whether maturation and relative age interact with time during adolescence to differentially affect the development of anthropometric and fitness characteristics in junior rugby league players.
O'Hara, J, Chapman, C, Cobley, S, Cobley, S., Cooke, Carlton, Chapman, C., Till, K, Cooke, CB, Till, K., O' Hara, J.   +9 more
core   +1 more source

MRamirez1414/Cochlear-ribbon-synapse-maturation-requires-Nlgn1-and-Nlgn3: Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3

, 2022
Code associated with Cochlear ribbon synapse maturation requires Nlgn1 and ...
MRamirez1414
core   +1 more source

Polymorphisms in Gag spacer peptide 1 confer varying levels of resistance to the HIV-1 maturation inhibitor bevirimat [PDF]

, 2010
Background: The maturation inhibitor bevirimat (BVM) potently inhibits human immunodeficiency virus type 1 (HIV-1) replication by blocking capsid-spacer peptide 1 (CA-SP1) cleavage. Recent clinical trials demonstrated that a significant proportion of HIV-
Sakalian Michael, Karl Salzwedel, Salzwedel Karl, Catherine S. Adamson, Eric O. Freed, Sakalian, M, Michael Sakalian, Adamson, Catherine S, Salzwedel, K, Freed Eric O, Freed, E.O., Adamson Catherine S   +11 more
core   +1 more source

Structural maturation of the HIV-1 RNA 5' untranslated region by Pr55 Gag and its maturation products

, 2022
International audienceMaturation of the HIV-1 viral particles shortly after budding is required for infectivity. During this process, the Pr55 Gag precursor undergoes a cascade of proteolytic cleavages, and whilst the structural rearrangements of the ...
Smyth, Redmond P, Tisné, Carine, Mouhand, Assia, Smyth, Redmond, Mak, Johnson, Marquet, Roland, Gilmer, Orian, Mailler, Elodie, Paillart, Jean-Christophe, Vivet-Boudou, Valérie   +9 more
core   +1 more source

Maturity and maturity models in lean construction

Construction Economics and Building, 2014
In recent years there has been an increasing interest in maturity models in management-related disciplines; which reflects a growing recognition that becoming more mature and having a model to guide the route to maturity can help organisations in managing major transformational change.
Nesensohn, Claus, Bryde, David James, Ochieng, Edward, Fearon, Damian   +3 more
openaire   +5 more sources

Exceptional increase in the creep life of magnesium rare-earth alloys due to localized bond stiffening

Nature Communications, 2017
Adding very small amounts of zinc to magnesium alloys containing rare earth elements dramatically improves their creep life. Here, the authors use first principles calculations and atomic-scale characterization to show that this is due to stiff covalent ...
Deep Choudhuri, Srivilliputhur G. Srinivasan, Mark A. Gibson, Yufeng Zheng, David L. Jaeger, Hamish L. Fraser, Rajarshi Banerjee   +6 more
doaj   +1 more source

In Vitro Maturation of Oocytes in Women at Risk of Ovarian Hyperstimulation Syndrome-A Prospective Multicenter Cohort Study [PDF]

International Journal of Fertility and Sterility, 2019
Background: In vitro maturation (IVM) is an artificial reproductive technology in which immature oocytes are harvested from the ovaries and subsequently will be matured in vitro.
Sanne C. Braam, Dimitri Consten, Jesper M.J. Smeenk, Ben J. Cohlen, Max H.J.M. Curfs, Carl J.C.M. Hamilton, Sjoerd Repping, Ben W.J. Mol, Jan Peter de Bruin   +8 more
doaj   +1 more source