Results 11 to 20 of about 1,501,264 (312)

The Role of Ca2 + in Maturation and Reprogramming of Bovine Oocytes: A System Study of Low-Calcium Model

open access: yesFrontiers in Cell and Developmental Biology, 2021
[Ca2+]i is essential for mammalian oocyte maturation and early embryonic development, as those processes are Ca2+ dependent. In the present study, we investigated the effect of [Ca2+]i on in vitro maturation and reprogramming of oocytes in a lower ...
Lin Meng   +9 more
doaj   +1 more source

Heterozygous premature termination in zinc-finger domain of Krüppel-like factor 2 gene associates with dysregulated immunity

open access: yesFrontiers in Immunology, 2022
Krüppel-like factor 2 (KLF2) is a transcription factor with significant roles in development, maturation, differentiation, and proliferation of several cell types.
Nora Pernaa   +18 more
doaj   +1 more source

Reticulocyte Maturation

open access: yesMembranes, 2022
Changes to the membrane proteins and rearrangement of the cytoskeleton must occur for a reticulocyte to mature into a red blood cell (RBC). Different mechanisms of reticulocyte maturation have been proposed to reduce the size and volume of the reticulocyte plasma membrane and to eliminate residual organelles.
Stevens-Hernandez, Christian J.   +1 more
openaire   +5 more sources

Pomalidomide enhances the maturation of dendritic cells derived from healthy donors and multiple myeloma patients

open access: yesFrontiers in Pharmacology, 2022
Objective: To explore the effect of pomalidomide on the maturation of monocyte-derived dendritic cells (moDCs) from healthy donors (HDs) and multiple myeloma (MM) patients.Methods: MoDCs were generated by the incubation of monocytes from peripheral blood
Xi Wang   +7 more
doaj   +1 more source

Validating expression of beta cell maturation-associated genes in human pancreas development

open access: yesFrontiers in Cell and Developmental Biology, 2023
The identification of genes associated with human pancreatic beta cell maturation could stimulate a better understanding of normal human islet development and function, be informative for improving stem cell-derived islet (SC-islet) differentiation, and ...
Daniel M. Tremmel   +7 more
doaj   +1 more source

Inflammatory-driven NK cell maturation and its impact on pathology

open access: yesFrontiers in Immunology, 2022
NK cells are innate lymphocytes involved in a large variety of contexts and are crucial in the immunity to intracellular pathogens as well as cancer due to their ability to kill infected or malignant cells.
Elsa Bourayou, Rachel Golub
doaj   +1 more source

The role of toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCs) - Peptidoglycan and lipoteichoic acid are inducers of DC maturation and require TLR2 [PDF]

open access: yes, 2001
Toll-like receptors (TLRs) have been found to be key elements in pathogen recognition by the host immune system. Dendritic cells (DCs) are crucial for both innate immune responses and initiation of acquired immunity.
Aicher, A   +6 more
core   +1 more source

Differential rates of perinatal maturation of human primary and nonprimary auditory cortex [PDF]

open access: yes, 2018
Primary and nonprimary cerebral cortex mature along different timescales; however, the differences between the rates of maturation of primary and nonprimary cortex are unclear.
Brownell, Abraham   +9 more
core   +2 more sources

Transcriptomic Analysis Identifies Differentially Expressed Genes Associated with Vascular Cuffing and Chronic Inflammation Mediating Early Thrombosis in Arteriovenous Fistula

open access: yesBiomedicines, 2022
Arteriovenous fistula (AVF) is vascular access created for hemodialysis in end-stage renal disease patients. AVF creation causes increased blood flow in the outflow vein with increased pressure. Increased blood flow, blood volume, and shear stress causes
Vikrant Rai, Devendra K. Agrawal
doaj   +1 more source

Surface Functionalization of Silica Nanoparticles: Strategies to Optimize the Immune-Activating Profile of Carrier Platforms

open access: yesPharmaceutics, 2022
Silica nanoparticles (SiNPs) are generally regarded as safe and may represent an attractive carrier platform for nanomedical applications when loaded with biopharmaceuticals. Surface functionalization by different chemistries may help to optimize protein
Benjamin Punz   +6 more
doaj   +1 more source

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