Results 31 to 40 of about 895,186 (317)
Vaccines, 2023 Although aluminium-based vaccines have been used for almost over a century, their mechanism of action remains unclear. It is established that antigen adsorption to the adjuvant facilitates delivery of the antigen to immune cells at the injection site. To
Donatello Laera +7 more
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Animals, 2021 Embryo production is a routine procedure in several species. However, in felids, the effectiveness of this approach is far behind that in the majority of laboratory species.
Lorena Fernandez-Gonzalez +5 more
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Viruses, 2022 Previously, we reported that an HIV-1 variant containing Met-to-Ile change at codon 50 and Val-to-Ile mutation at codon 151 of integrase (IN), HIV(IN:M50I/V151I), was an impaired virus.
Tomozumi Imamichi +4 more
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Pharmaceuticals, 2022 Pediatric cancer treatment has evolved significantly in recent decades. The implementation of risk stratification strategies and the selection of evidence-based chemotherapy combinations have improved survival outcomes.
Ashwin Kamath +5 more
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HIV-1 Maturation: Lessons Learned from Inhibitors
Viruses, 2020 Since the emergence of HIV and AIDS in the early 1980s, the development of safe and effective therapies has accompanied a massive increase in our understanding of the fundamental processes that drive HIV biology.
Alex B. Kleinpeter, Eric O. Freed
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Aquatic Living Resources, 2021 The maturation of anadromous whitefish (Coregonus lavaretus) was analysed from samples taken from commercial coastal fishing in 1998–2014 in the Gulf of Bothnia. Whitefish matured at a younger age from year to year.
Veneranta Lari +3 more
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Frontiers in Bioscience-Scholar, 2022 While the primary purpose of radiotherapy (RT) is the elimination of cancer cells by inducing DNA-damage, considerable evidence emerges that anti-neoplastic effects extend beyond mere tumor cell killing. These secondary effects are based on activation of
Laila König +7 more
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Cell Stem Cell, 2021 Alveolar type 2 cells are recognized as epithelial progenitors of the lung gas-exchange region. In this issue of Cell Stem Cell, Penkala et al. (2021) provide evidence that this is not so during neonatal life, and that alveolar type I cell reprograming is a key event during regeneration post-hyperoxia injury.
openaire +3 more sources
Rab3D is critical for secretory granule maturation in PC12 cells.
, 2013 Neuropeptide- and hormone-containing secretory granules (SGs) are synthesized at the trans-Golgi network (TGN) as immature secretory granules (ISGs) and complete their maturation in the F-actin-rich cell cortex.
Sharon A. Tooze (391543) +36 more
core +1 more source
Maturation of retroviruses [PDF]
Current Opinion in Virology, 2019 During retrovirus maturation, cleavage of the precursor structural Gag polyprotein by the viral protease induces architectural rearrangement of the virus particle from an immature into a mature, infectious form. The structural rearrangement encapsidates the viral RNA genome in a fullerene capsid, producing a diffusible viral core that can initiate ...
Owen, Pornillos +1 more
openaire +2 more sources