Advanced Functional Materials, EarlyView.This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann +2 more
wiley +1 more source
Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers
Advanced Functional Materials, EarlyView.A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley +1 more source
A Comprehensive Perspective on the Biological Effects of Intermittent Fasting and Periodic Short-Term Fasting: A Promising Strategy for Optimizing Metabolic Health. [PDF]
NutrientsCiastek B, Kapłon K, Domaszewski P.
europepmc +1 more source
Advanced Functional Materials, EarlyView.We present a fully automated Bayesian optimization (BO) protocol for the parameterization of nonbonded interactions in coarse‐grain CG force fields (BACH). Using experimental thermophysical data, we apply the protocol to a broad range of liquids, spanning linear, branched, and unsaturated hydrocarbons, esters, triglycerides, and water.
Janak Prabhu +3 more
wiley +1 more source
Biosynthesis of mitochondrial proteins in the cytoplasm and their transport to the mitochondrial membrane [PDF]
, 1978 Neupert, Walter
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LL‐37 Driven Phase Transition and Stacking in Oligolamellar Gram‐Negative Bacterial Membrane Models
Advanced Functional Materials, EarlyView.This work establishes oligolamellar bacterial membrane models to investigate how LL‐37 disrupts the complex dual‐bilayer architecture of Gram‐negative bacteria. Combining SAXS, cryo‐TEM, electrophoretic mobility measurements, and coarse‐grained simulations, it reveals cardiolipin‐driven phase transitions leading to bicelle‐like structures and membrane ...
Bettina Tran +5 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Butterfly wing scales are intricate cuticular functional nanosctructures. This perspective suggests that spatially varying material properties, cytoskeletal constraints, and growth‐driven mechanical instabilities shape the resulting nanoscale architectures created from single cells.
Anupama Prakash +10 more
wiley +1 more source
Meßbare Veränderungen in bestrahlten Lebensmitteln - Anwendung chromatographischer, elektrophoretischer und spektralphotometrischer Methoden zur Untersuchung von Aromastoffen, Aminosäuren, Fettsäuren, Naturfarbstoffen und Enzymen. EUR 4617. = Measurable changes in irradiated foodstuffs - Use of chromatographic, electrophoretic and spectro-photometric methods for the analysis of aromatics, fatty acids, natural dyes and enzymes. EUR 4617. [PDF]
, 1971 Drawert, F. +4 more
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Robust Polymer Hydrogels Improve Electric‐Fish‐Inspired Batteries
Advanced Functional Materials, EarlyView.ABSTRACT Electric‐fish‐inspired hydrogel batteries based on ion‐concentration gradients offer an attractive route to soft power sources; however, the poor mechanical properties of existing hydrogels limit device assembly and performance. Here, we report poly(ethylene glycol) methyl ether acrylate hydrogels that enable ion‐gradient batteries composed of
Nick Zahnd +5 more
wiley +1 more source