Results 121 to 130 of about 949 (209)
Abstract A mixed‐method heat acclimation (HA) protocol may optimise performance by supporting the training taper while promoting thermal adaptation; however, the impact on cardiovascular and fluid‐regulatory adjustments to protect health is unknown. Therefore, we examined the effects of a mixed‐method heat protocol on physiological responses, including
Daniel Snape +5 more
wiley +1 more source
One day of environment‐induced heat stress causes injury to the murine kidney
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths +3 more
wiley +1 more source
Abstract Older adults with reduced thermoregulatory capabilities are increasingly at risk of heat‐related pathophysiological outcomes (e.g., acute kidney injury, heatstroke) due to increasingly frequent, prolonged and intense heatwaves. Foot immersion and neck cooling have been proposed as practical, non‐electrical cooling strategies for protecting ...
Thomas McCarthy +7 more
wiley +1 more source
Copyright information:Taken from "Distantly related lipocalins share two conserved clusters of hydrophobic residues: use in homology modeling"http://www.biomedcentral.com/1472-6807/8/1BMC Structural Biology 2008;8():1-1.Published online 11 Jan 2008PMCID ...
Benoit Charloteaux (87758) +6 more
core +1 more source
Pets, furry animal allergen components, and asthma in childhood
Background The use of component‐resolved allergy diagnostics has provided a clearer understanding of the species‐specific sensitization and severity of potential allergic reactions.
Katariina Lajunen +8 more
doaj +1 more source
Mammalian tears are produced by lacrimal glands to protect eyes and to function in chemical communication and immunity. However, excess tears flow through nasolacrimal ductsto nasal tissues, and via the nasopharyngeal duct to the oral cavity where ...
Romana Stopkova +3 more
core +1 more source
Tripterine liposome (TP‐lipo) exerts anti‐pancreatic ductal adenocarcinoma (PDAC) effects through direct suppression of tumor cells and modulation of the tumor microenvironment (TME). TP‐lipo induces apoptosis and inhibits the clonogenicity, migration, and invasion of KPC cells in vitro.
Lirui Tang +8 more
wiley +1 more source
Our study reveals a novel mechanism by which MSC‐derived EVs alleviate NaIO3‐induced dry AMD‐like pathology. MSC‐EVs deliver miR‐486‐3p into retinal cells to directly inhibit the ferroptosis‐promoting target gene Lcn2. Concurrently, downregulated Lcn2 restores intracellular Gpx4 expression, thereby suppressing ferroptosis and rescuing retinal ...
Zheng Li +6 more
wiley +1 more source
The activation of fatty acids to their acyl-CoA derivatives is a crucial step for their integration into more complex lipids or their degradation via beta-oxidation.
Aslihan Ekim Kocabey (17739546) +1 more
core +1 more source
RNA‐seq and Batelli gland proteomics of fifth‐instar Mahanarva spectabilis nymphs reveal transcripts and proteins associated with xylem feeding, foam production and environmental interaction. Functional annotation identified genes involved in osmoregulation, detoxification, chemosensation and stress responses, while proteomic analysis confirmed ...
Monique da Silva Bonjour +8 more
wiley +1 more source

