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Lipocalins as biochemical markers of disease
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2000Lipocalins as biochemical markers of disease have been used extensively. The clinical indications relate to almost any field of medicine, such as inflammatory disease, cancer, lipid disorders, liver and kidney function. Some of the more well-known lipocalins that have been used as markers of disease are orosomucoid, Protein HC (alpha(1)-microglobulin),
S, Xu, P, Venge
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The role of lipocalins in airway disease
Clinical & Experimental Allergy, 2013SummaryThe pathogenesis of allergic airway inflammation and disease is complex and still not fully understood. Many cells, factors and mediators are involved in the different aspects of induction, maintenance and persistence of airway inflammation. The heterogeneity and redundancy of this system is one of the main reasons why novel therapeutic targets ...
A M, Dittrich, H A, Meyer, E, Hamelmann
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Tear lipocalins bind a broad array of lipid ligands
Current Eye Research, 1995Wayne Hubbell +2 more
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Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2000
We introduce a website devoted to the lipocalins. The website contains data on lipocalin structures and sequences, as well as reviewing lipocalin biology and biochemistry. Our hope is that it can act as a focus for future research into the lipocalin protein family. The website can be accessed at the following URL: http://www. jenner.ac.uk/lipocalin.htm.
K, Paine, D R, Flower
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We introduce a website devoted to the lipocalins. The website contains data on lipocalin structures and sequences, as well as reviewing lipocalin biology and biochemistry. Our hope is that it can act as a focus for future research into the lipocalin protein family. The website can be accessed at the following URL: http://www. jenner.ac.uk/lipocalin.htm.
K, Paine, D R, Flower
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Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2000
The term allergy refers to clinical conditions caused by an inappropriate immune response to innocuous proteins in genetically predisposed persons. Allergens of animal origin are responsible for a significant proportion of allergies. In recent years, it has become evident that practically all respiratory animal allergens characterized at the molecular ...
R, Mäntyjärvi +2 more
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The term allergy refers to clinical conditions caused by an inappropriate immune response to innocuous proteins in genetically predisposed persons. Allergens of animal origin are responsible for a significant proportion of allergies. In recent years, it has become evident that practically all respiratory animal allergens characterized at the molecular ...
R, Mäntyjärvi +2 more
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Allergy, 2001
Most animal‐derived major allergens causing respiratory sensitization belong to the family of proteins called lipocalins. Their sequential identity varies but the three‐dimensional structure is conserved. They are present in body fluids and secretions. Several lipocalins are able to bind and transport small hydrophobic ligands like retinol.
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Most animal‐derived major allergens causing respiratory sensitization belong to the family of proteins called lipocalins. Their sequential identity varies but the three‐dimensional structure is conserved. They are present in body fluids and secretions. Several lipocalins are able to bind and transport small hydrophobic ligands like retinol.
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Current Allergy and Asthma Reports, 2012
Lipocalins represent the most important group of inhalant animal allergens. For some of them, three-dimensional protein structures have been resolved, but their functions are still elusive. Lipocalins generally display a low sequence identity between family members.
Christiane, Hilger +2 more
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Lipocalins represent the most important group of inhalant animal allergens. For some of them, three-dimensional protein structures have been resolved, but their functions are still elusive. Lipocalins generally display a low sequence identity between family members.
Christiane, Hilger +2 more
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Neutrophil gelatinase-associated lipocalin
Current Opinion in Critical Care, 2010Acute kidney injury (AKI) is a major clinical problem in hospitalized patients. Effective treatment and early diagnosis of this syndrome are not currently available. This review focuses on recent studies examining the biological characteristics and the diagnostic and prognostic value of a novel biomarker--neutrophil gelatinase-associated lipocalin ...
Michael, Haase +2 more
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