Results 31 to 40 of about 30,056 (201)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Endoscopic En-Bloc Resection of Lipoma of the Tibialis Anterior Tendon

Arthroscopy Techniques, 2023
Lipoma is benign soft-tissue tumor that consists entirely of mature fat and can occur in a superficial or deep location. Lipoma of the foot and ankle can even develop within a tendon sheath or joint.
On Fai Arthur Woo, M.B.Ch.B. (Glasg.), B.Sc. (Med. Sci.), M.R.C.S. (Glasg.), Tun Hing Lui, M.B.B.S. (H.K.), F.R.C.S. (Edin.), F.H.K.A.M., F.H.K.C.O.S.   +1 more
doaj   +1 more source

Intramuscular (infiltrating) Lipoma [PDF]

, 2011
Intraoral lipomas are benign and relatively rare tumors, although they occur with higher frequencies in other areas, most especially the back, abdomen and shoulders of adults.
P Sridhar Reddy,, Kashyap, Bina, Bina Kashyap,, Naag, Ananth, Reddy, P Sridhar, Ananth Naag,   +5 more
core  

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

Advanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao   +5 more
wiley   +1 more source

Frontal parosteal lipoma with thickening of diploic space

JPRAS Open, 2015
Parosteal lipoma is a rare benign tumor that is composed mainly of benign mature lipocytes, and it has an intimate association with the underlying affected bone.
Tsuyoshi Morishita, Kazuhiro Toriyama, Shunjiro Yagi, Keisuke Takanari, Masazumi Fujii, Yoshihiro Nishida, Seiichi Kato, Yuzuru Kamei   +7 more
doaj   +1 more source

Intramuscular Lipoma of the Pectoralis Major Simulating a Breast Lump [PDF]

Journal of Clinical and Diagnostic Research, 2019
Intramuscular lipoma is a deep-seated lipoma that arises in the muscle and is benign and relatively rare. Intramuscular lipomas of the pectoralis major muscle have been reported to mimic malignant breast tumours.
Rajendra Benakatti, Dinesh Bangalore, Pavan Bhat   +2 more
doaj   +1 more source

Fine‐Needle Aspiration of Salivary Gland Tumors With Low‐Grade Oncocytic Features: Focusing on Oncocytoma Versus Oncocytic Mucoepidermoid Carcinoma

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Salivary gland fine‐needle aspirates (FNAs) with low‐grade oncocytic features are diagnostically challenging due to the substantial morphologic overlap between benign oncocytic tumors and their malignant mimickers. This study evaluates the diagnostic discriminators, performance, and risk of malignancy of these lesions using the ...
Lois Araneta, Ying‐Ju Kuo, Jen‐Fan Hang   +2 more
wiley   +1 more source

Clinical and genetic features of pediatric hereditary polyposis syndromes in Israel: A nationwide multicenter cohort

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Hereditary polyposis syndromes in children are rare, heterogeneous disorders associated with significant morbidity and long‐term risk of malignancy. Current data on their presentation, management, and outcomes in pediatric populations remain limited.
Shlomi Cohen, Tal Cozacov, Ilana Weintraub, Ron Shaoul, Oren Ledder, Dotan Yogev, Mordechai Slae, Ranya Egbarieh, Galina Ling, Anat Yerushalmy‐Feler   +9 more
wiley   +1 more source

Primary scrotal lipoma in a child: a rare case report and review of literature

Frontiers in Pediatrics
Lipoma is a common benign tumor of the body surface, while scrotal lipoma is relatively rare. We report a case of scrotal lipoma in a 5-year-old boy, which presented as a progressively enlarging scrotal mass.
Meng Kong, Meng Kong, Yuexia Bai, Jinhua Jia, Jinhua Jia, Chuanyang Liu, Chuanyang Liu, Shisong Zhang, Shisong Zhang   +8 more
doaj   +1 more source

Intradural Lipoma at the Craniocervical Junction Presenting with Progressing Hemiparesis: A Case Report

Case Reports in Neurology, 2019
Intradural spinal lipomas are rare in an adult population. They are mostly asymptomatic and usually associated with spinal dysraphism in a pediatric population. We report a rare case of spinal lipoma without dysraphism and with progressing hemiparesis. A
Takuro Inoue, Hisao Hirai, Ayako Shima, Fumio Suzuki, Masayuki Matsuda, Takanori Fukushima   +5 more
doaj   +1 more source