Results 141 to 150 of about 640,235 (385)

Geometrically Tunable Scaffold‐Free Muscle Bioconstructs for Treating Volumetric Muscle Loss

Advanced Healthcare Materials, EarlyView.
Volumetric muscle loss is associated with traumatic muscle resulting in permanent functional impairment. Mold‐based, scaffold‐free, high‐density muscle tissue bioconstructs are developed in customizable geometric shapes and sizes. The transplanted rectangular solid‐shaped muscle bioconstructs improved muscle force recovery and tissue regeneration in ...
Bugra Ayan, Gaoxian Chen, Ishita Jain, Sha Chen, Gladys Chiang, Caroline Hu, Renato Reyes, Beu P. Oropeza, Ngan F. Huang   +8 more
wiley   +1 more source

Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages

Journal of Lipid Research, 2003
Several of the ATP binding cassette (ABC) transporters have recently been shown to play important roles in reverse cholesterol transport (RCT) and prevention of atherosclerosis.
Weerapan Khovidhunkit, Arthur H. Moser, Judy K. Shigenaga, Carl Grunfeld, Kenneth R. Feingold   +4 more
doaj   +1 more source

Mechanisms to Evade the Phagocyte Respiratory Burst Arose by Convergent Evolution in Typhoidal Salmonella Serovars. [PDF]

, 2018
Typhoid fever caused by Salmonella enterica serovar (S.) Typhi differs in its clinical presentation from gastroenteritis caused by S. Typhimurium and other non-typhoidal Salmonella serovars.
Bäumler, Andreas J, Cobb, Brian A, Hiyoshi, Hirotaka, Lock, Gabriel, Raffatellu, Manuela, Saechao, Cheng, Wangdi, Tamding   +6 more
core   +2 more sources

Inhalability and Bioactivity of Spray‐Dried versus Pressurized Gas eXpanded Liquid Technology‐Processed Yeast Beta‐Glucan Microparticles for Anti‐Fibrotic Therapies

Advanced Healthcare Materials, EarlyView.
PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Nate Dowdall, Safaa Naiel, Quan Zhou, Pareesa Ali, Tamana Rubina Yousof, Emily Wong, Ricardo Couto, Byron Yépez, Bernhard Seifried, Paul Moquin, Rod Rhem, Myrna Dolovich, Martin Rainer Kolb, Kjetil Ask, Todd Hoare   +14 more
wiley   +1 more source

Subcellular organelle lipidomics in TLR-4-activated macrophages1[S]

Journal of Lipid Research, 2010
Lipids orchestrate biological processes by acting remotely as signaling molecules or locally as membrane components that modulate protein function. Detailed insight into lipid function requires knowledge of the subcellular localization of individual ...
Alexander Y. Andreyev, Eoin Fahy, Ziqiang Guan, Samuel Kelly, Xiang Li, Jeffrey G. McDonald, Stephen Milne, David Myers, Hyejung Park, Andrea Ryan, Bonne M. Thompson, Elaine Wang, Yihua Zhao, H. Alex Brown, Alfred H. Merrill, Christian R.H. Raetz, David W. Russell, Shankar Subramaniam, Edward A. Dennis   +18 more
doaj   +1 more source

High Glucose and Lipopolysaccharide Prime NLRP3 Inflammasome via ROS/TXNIP Pathway in Mesangial Cells

Journal of Diabetes Research, 2016
While inflammation is considered a central component in the development in diabetic nephropathy, the mechanism remains unclear. The NLRP3 inflammasome acts as both a sensor and a regulator of the inflammatory response.
H. Feng, Junling Gu, F. Gou, Wei Huang, Chenlin Gao, Guo Chen, Y. Long, Xueqin Zhou, Maojun Yang, Shuang Liu, Shishi Lü, Qiaoyan Luo, Yong Xu   +12 more
semanticscholar   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun, Elizabeth S. Nakasone, Ha Eun Shin, Hyojin Lee, Jong‐Chan Park, Wonhwa Lee, Wooram Park, Chun Gwon Park, Juwon Park, Se‐Na Kim   +9 more
wiley   +1 more source

The Effects of Proteolytic Enzymes on Agglutination by Bacterial Antibodies of Lipopolysaccharide Modified Erythrocytes [PDF]

, 1959
E. Neter, E. Cohen, Otto Westphal, O. Lüderitz   +3 more
openalex   +1 more source

Characterization of the Lipopolysaccharide from a \u3cem\u3eRhizobium phaseoli\u3c/em\u3e Mutant that is Defective in Infection Thread Development [PDF]

, 1987
The lipopolysaccharide (LPS) from a Rhizobium phaseoli mutant, CE109, was isolated and compared with that of its wild-type parent, CE3. A previous report has shown that the mutant is defective in infection thread development, and sodium dodecyl sulfate ...
Carlson, Russell W., Kalembasa, Stanislaw, Noel, K. Dale, Pachori, Pappi, Turowski, Debra A.   +4 more
core   +1 more source

Immune cells and preterm labour:do invariant NKT cells hold the key? [PDF]

, 2015
We have developed our original made-to-measure (M2M) algorithm, PRIMAL, with the aim of modelling the Galactic disc from upcoming Gaia data. From a Milky Way like N-body disc galaxy simulation, we have created mock Gaia data using M0III stars as tracers,
Rinaldi, S F, Rossi, A G, Saunders, Philippa, Norman, J E   +3 more
core   +3 more sources