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Lipopolysaccharide-Dependent and Lipopolysaccharide-Independent Pathways of Monocyte Desensitisation to Lipopolysaccharides

Journal of Leukocyte Biology, 1991
Abstract The present study demonstrates that with time in culture blood monocytes (MO) lose their ability to express procoagulant activity (PCA) and secrete tumor necrosis factor-alpha (TNFα) in culture medium in response to lipopolysaccharide (LPS) stimulation.
Flora S. Baranova, Alexander Y. Annenkov
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LIPOPOLYSACCHARIDE RECOGNITION, CD14, AND LIPOPOLYSACCHARIDE RECEPTORS

Infectious Disease Clinics of North America, 1999
The ability of a host to sense invasion by a pathogenic organism, and to respond appropriately to control infection, is paramount to survival. To that end, an array of receptors and binding proteins has evolved as part of the innate immune system to detect Gram-negative bacteria.
Douglas T. Golenbock   +4 more
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Lipopolysaccharides of Rhizobium

Archives of Microbiology, 1980
Hot phenol-water extractions were carried out of cells from 12 strains of the fast-growing rhizobia Rhizobium leguminosarum, Rhizobium phaseoli, Rhizobium trifolii and Rhizobium meliloti. Purified lipopolysaccharide preparations contain neutral sugars, hexosamines, 2-keto-3-deoxyoctonate and uronic acids.
Zevenhuizen, L.P.T.M.   +2 more
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Lipopolysaccharides ofShigella sonnei [PDF]

open access: possibleApplied Biochemistry and Microbiology, 2000
Immunobiological properties of native lipopolysaccharides (LPS) from virulent and avirulent strains of Shigella sonnei bacteria (LPS-V and LPS-A, respectively) were studied. In avirulent bacteria, LPS-V induced immunosuppressive activity specific of the virulent strain. LPS of the avirulent strain, whereas LPS-A lacked this property.
V. A. Borisov, E. V. Borisova
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PATHOBIOLOGY OF LIPOPOLYSACCHARIDE

Journal of Toxicology and Environmental Health, 1997
Lipopolysaccharide is a component of the gram-negative bacterial cell wall that is responsible for 25,000-50,000 deaths in the United States each year. The sequelae of gram-negative infection and septicemia leading to death include fever, hypotension with inadequate tissue perfusion, and disseminated intravascular coagulation.
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A Lipopolysaccharide Antigen of the Treponema

Nature, 1958
IMMUNOCHEMICAL studies carried out by D'Alessandro et al. 1 on a non-pathogenic, culturable treponeme, the so-called Reiter treponeme, revealed the presence of four antigenic components: (1) a thermolabile protein; (2) a specific, thermostable antigen with polysaccharide characteristics; (3) a lipoid, corresponding to the ubiquitous lipidic antigen ...
Giuseppe D'alessandro, Carla Del Carpio
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Structure of bacterial lipopolysaccharides

Carbohydrate Research, 2003
Bacterial lipopolysaccharides are the major components of the outer surface of Gram-negative bacteria They are often of interest in medicine for their immunomodulatory properties. In small amounts they can be beneficial, but in larger amounts they may cause endotoxic shock.
D Karibian, Martine Caroff
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