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SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells

Animal Models and Experimental Medicine, EarlyView.
The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang, Xuepei Lei, Yiying Huang, Jiaming Tang, Guiying Shi, Hang Li, Lin Bai   +6 more
wiley   +1 more source

Cumambrin B Alleviates Sepsis-Associated Acute Lung Injury by Activating the Nrf2/HO-1 Pathway. [PDF]

Biomedicines
Que Y, Ruan D, Xu M, Nie Y, Huang G, Zhao H, Yang Y.   +6 more
europepmc   +1 more source

Efficacy of Nebulized Pentoxifylline in a Mouse Model of Emphysema Induced by Cigarette Smoke and Aerosolized Lipopolysaccharide. [PDF]

Int J Chron Obstruct Pulmon Dis
Hu Z, Yu Y, Peng T, Niu R, Li Z, Wang W, Zheng X, Zhang J.   +7 more
europepmc   +1 more source

Amphiregulin attenuates sepsis-induced myocardial dysfunction by maintaining the localization of connexin43. [PDF]

Inflamm Regen
Chen M, Takamori S, Isayama K, Wang Y, Matsunaga S, Narahara S, Honsho M, Murata M, Kinugawa S, Abe K, Akahoshi T.   +10 more
europepmc   +1 more source

RETRACTION: Systems Pharmacology Reveals the Mechanism of Activity of Physalis alkekengi L. var. Franchetii Against Lipopolysaccharide-Induced Acute Lung Injury. [PDF]

J Cell Mol Med
europepmc   +1 more source

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Lipopolysaccharide-Dependent and Lipopolysaccharide-Independent Pathways of Monocyte Desensitisation to Lipopolysaccharides

Journal of Leukocyte Biology, 1991
Abstract The present study demonstrates that with time in culture blood monocytes (MO) lose their ability to express procoagulant activity (PCA) and secrete tumor necrosis factor-alpha (TNFα) in culture medium in response to lipopolysaccharide (LPS) stimulation.
A Y, Annenkov, F S, Baranova
openaire   +2 more sources

Lipopolysaccharides

2021
André M. Lopes, Jorge Fernando Brandão Pereira, João V. D. Molino, Felipe R. Lourenço, Adalberto Pessoa   +4 more
openaire   +1 more source