Results 1 to 10 of about 138,148 (264)

Incorporation of Spike and Membrane Glycoproteins into Coronavirus Virions [PDF]

open access: yesViruses, 2015
The envelopes of coronaviruses (CoVs) contain primarily three proteins; the two major glycoproteins spike (S) and membrane (M), and envelope (E), a non-glycosylated protein.
Makoto Ujike, Fumihiro Taguchi
doaj   +2 more sources

Two Sides to Every Story: Herpes Simplex Type-1 Viral Glycoproteins gB, gD, gH/gL, gK, and Cellular Receptors Function as Key Players in Membrane Fusion

open access: yesViruses, 2021
Herpes simplex virus type-1 (HSV-1) and type-2 (HSV-2) are prototypical alphaherpesviruses that are characterized by their unique properties to infect trigeminal and dorsal root ganglionic neurons, respectively, and establish life-long latent infections.
Nithya Jambunathan   +5 more
doaj   +3 more sources

Receptor-Targeted Nipah Virus Glycoproteins Improve Cell-Type Selective Gene Delivery and Reveal a Preference for Membrane-Proximal Cell Attachment. [PDF]

open access: yesPLoS Pathogens, 2016
Receptor-targeted lentiviral vectors (LVs) can be an effective tool for selective transfer of genes into distinct cell types of choice. Moreover, they can be used to determine the molecular properties that cell surface proteins must fulfill to act as ...
Ruben R Bender   +7 more
doaj   +3 more sources

Glycoproteins of the lysosomal membrane. [PDF]

open access: yesJournal of Cell Biology, 1985
Three glycoprotein antigens (120, 100, and 80 kD) were detected by mono- and/or polyclonal antibodies generated by immunization with highly purified rat liver lysosomal membranes. All of the antigens were judged to be integral membrane proteins based on the binding of Triton X-114.
Mark Marsh, Mellman I, Helenius A
exaly   +3 more sources

TMEM259/MEMBRALIN is a non-canonical ER-phagy receptor that associates with MAN1B1 and VCP to eliminate viral glycoproteins [PDF]

open access: yesAutophagy Reports
Selective autophagy of the endoplasmic reticulum (ER-phagy/reticulophagy) is essential for organelle homeostasis and host defense, yet how ER quality control (ERQC) pathways distinguish viral glycoproteins from misfolded host proteins remains poorly ...
Jim Maurice Camilleri   +5 more
doaj   +2 more sources

Glycan structures contain information for the spatial arrangement of glycoproteins in the plasma membrane. [PDF]

open access: yesPLoS ONE, 2013
Glycoconjugates at the cell surface are crucial for cells to communicate with each other and the extracellular microenvironment. While it is generally accepted that glycans are vectorial biopolymers, their information content is unclear.
M Kristen Hall   +4 more
doaj   +1 more source

Tamoxifen-resistant breast cancer cells exhibit reactivity with Wisteria floribunda agglutinin.

open access: yesPLoS ONE, 2022
Glycosylation is one of the most important post-translational modifications of cell surface proteins involved in the proliferation, metastasis and treatment resistance of cancer cells.
May Thinzar Hlaing   +11 more
doaj   +1 more source

Structures of the Hepaci-, Pegi-, and Pestiviruses envelope proteins suggest a novel membrane fusion mechanism.

open access: yesPLoS Biology, 2023
Enveloped viruses encode specialised glycoproteins that mediate fusion of viral and host membranes. Discovery and understanding of the molecular mechanisms of fusion have been achieved through structural analyses of glycoproteins from many different ...
Michael R Oliver   +5 more
doaj   +1 more source

Neutrophil azurophilic granule glycoproteins are distinctively decorated by atypical pauci- and phosphomannose glycans

open access: yesCommunications Biology, 2021
Reiding et al. performed conventional proteomics as well as glycoproteomics on protein extracts from lysates of pooled neutrophils obtained from ten healthy donors.
Karli R. Reiding   +4 more
doaj   +1 more source

Antibody binding reports spatial heterogeneities in cell membrane organization

open access: yesNature Communications, 2023
The spatial organization of cell membrane glycoproteins and glycolipids is critical for mediating the binding of ligands, receptors, and macromolecules on the plasma membrane.
Daniel P. Arnold   +2 more
doaj   +1 more source

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