Incorporation of Spike and Membrane Glycoproteins into Coronavirus Virions [PDF]
The envelopes of coronaviruses (CoVs) contain primarily three proteins; the two major glycoproteins spike (S) and membrane (M), and envelope (E), a non-glycosylated protein.
Makoto Ujike, Fumihiro Taguchi
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Retinal glycoprotein enrichment by concanavalin a enabled identification of novel membrane autoantigen synaptotagmin-1 in equine recurrent uveitis. [PDF]
Complete knowledge of autoantigen spectra is crucial for understanding pathomechanisms of autoimmune diseases like equine recurrent uveitis (ERU), a spontaneous model for human autoimmune uveitis. While several ERU autoantigens were identified previously,
Margarete E Swadzba +4 more
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Herpesvirus glycoproteins undergo multiple antigenic changes before membrane fusion.
Herpesvirus entry is a complicated process involving multiple virion glycoproteins and culminating in membrane fusion. Glycoprotein conformation changes are likely to play key roles.
Daniel L Glauser +2 more
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TMEM259/MEMBRALIN is a non-canonical ER-phagy receptor that associates with MAN1B1 and VCP to eliminate viral glycoproteins [PDF]
Selective autophagy of the endoplasmic reticulum (ER-phagy/reticulophagy) is essential for organelle homeostasis and host defense, yet how ER quality control (ERQC) pathways distinguish viral glycoproteins from misfolded host proteins remains poorly ...
Jim Maurice Camilleri +5 more
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Biogenesis of hepatocyte plasma-membrane domains. Incorporation of (3H)fucose into plasma-membrane and golgi-apparatus glycoproteins [PDF]
1. Rats were injected intracaudally with [3H]fucose and its rate of incorporation into the fucoproteins of serum, Golgi and plasma-membrane subfractions was followed for up tp 2h. 2.
Evans, William Howard +2 more
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Herpes simplex virus type-1 (HSV-1) and type-2 (HSV-2) are prototypical alphaherpesviruses that are characterized by their unique properties to infect trigeminal and dorsal root ganglionic neurons, respectively, and establish life-long latent infections.
Nithya Jambunathan +5 more
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Glycan structures contain information for the spatial arrangement of glycoproteins in the plasma membrane. [PDF]
Glycoconjugates at the cell surface are crucial for cells to communicate with each other and the extracellular microenvironment. While it is generally accepted that glycans are vectorial biopolymers, their information content is unclear.
M Kristen Hall +4 more
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Tamoxifen-resistant breast cancer cells exhibit reactivity with Wisteria floribunda agglutinin.
Glycosylation is one of the most important post-translational modifications of cell surface proteins involved in the proliferation, metastasis and treatment resistance of cancer cells.
May Thinzar Hlaing +11 more
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Enveloped viruses encode specialised glycoproteins that mediate fusion of viral and host membranes. Discovery and understanding of the molecular mechanisms of fusion have been achieved through structural analyses of glycoproteins from many different ...
Michael R Oliver +5 more
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Reiding et al. performed conventional proteomics as well as glycoproteomics on protein extracts from lysates of pooled neutrophils obtained from ten healthy donors.
Karli R. Reiding +4 more
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