Results 1 to 10 of about 40,413 (292)
Platelet Membrane Glycoproteins: A Historical Review [PDF]
Seminars in Thrombosis and Hemostasis, 2014 The search for the components of the platelet surface that mediate platelet adhesion and platelet aggregation began for earnest in the late 1960s when electron microscopy demonstrated the presence of a carbohydrate-rich, negatively charged outer coat that was called the "glycocalyx." Progressively, electrophoretic procedures were developed that ...
Alan T Nurden
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Analysis of Platelet Membrane Glycoproteins and The Specific Antibodies in MYH9-Related Diseases [PDF]
International Journal of General MedicineLin Wang,1,2,* Ke Cao,3,* Shiyang Chen,3 Xiaoying Fu,3 Yunsheng Chen,3 Xiaojuan Luo1,3 1Shantou University School of Medicine, Shantou, Guangdong, 515000, People’s Republic of China; 2Department of Clinical Laboratory, The Seventh ...
Wang L +5 more
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Genetic determinants of arterial thrombosis in primary antiphospholipid syndrome: a systematic review [PDF]
Frontiers in ImmunologyBackgroundPrimary Antiphospholipid Syndrome (PAPS) is a systemic autoimmune disorder characterized by arterial and/or venous thrombosis and obstetric morbidity.
Claudia Gavris +3 more
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Molecular study of sticky platelet syndrome using exome sequencing
Revista de la Facultad de Medicina, 2021 Introduction: Sticky platelet syndrome (SPS) is a prothrombotic condition characterized by increased platelet aggregation that causes arterial and venous thrombosis.
Jaime José Pérez-Niño +5 more
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Platelet Membrane Glycoprofiling in a PMM2-CDG Patient
Journal of Inborn Errors of Metabolism and Screening, 2021 Congenital disorders of glycosylation (CDG) are metabolic hereditary diseases caused by defects in the synthesis of glycoconjugates. CDG have been described in sugar-nucleotide biosynthesis and transporter, glycosyltransferases, vesicular transport, as ...
G.M. Papazoglu +9 more
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Malaria Journal, 2020 Background Plasmodium falciparum malaria remains one of the world’s major infectious diseases that cause most morbidity and mortality, particularly in children.
Renate Asare +10 more
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Safflower Extract Inhibits ADP-Induced Human Platelet Aggregation
Plants, 2021 Safflower extract is commonly used as a traditional Chinese medicine to promote blood circulation and remove blood stasis. The antioxidant and anticancer properties of safflower extracts have been extensively studied, but their antiaggregative effects ...
Ping-Hsun Lu +6 more
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Two Arginine Residues of Streptococcus gordonii Sialic Acid-Binding Adhesin Hsa Are Essential for Interaction to Host Cell Receptors. [PDF]
PLoS ONE, 2016 Hsa is a large, serine-rich protein of Streptococcus gordonii DL1 that mediates binding to α2-3-linked sialic acid termini of glycoproteins, including platelet glycoprotein Ibα, and erythrocyte membrane protein glycophorin A, and band 3.
Yumiko Urano-Tashiro +3 more
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Platelet membrane glycoproteins: historical perspectives [PDF]
Journal of Thrombosis and Haemostasis, 2006 3–9. The function of blood platelets to prevent blood loss at injured sites in the vasculature depends largely on their capacity to adhere, aggregate, promote coagulation and secrete factors that induce vasoconstriction and recruit inflammatory cells. Produced in large numbers from megakaryocytes, platelets enter the circulation for 7–10 days primed to
A T, Nurden, D R, Phillips, J N, George
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Pathogenic mechanisms contributing to thrombocytopenia in patients with systemic lupus erythematosus
Platelets, 2022 Systemic lupus erythematosus (SLE) is an autoimmune condition developing thrombocytopenia in about 10–15% of cases, however, mechanisms leading to low platelet count were not deeply investigated in this illness.
M. Constanza Baroni Pietto +13 more
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