Results 291 to 300 of about 519,050 (337)

Evaluation of anti-inflammatory and neuroprotective effect of walnut shell pectin. [PDF]

Sci Rep
Sindhu O, Chandraprabha MN, Divyashri G, Murthy TPK.   +3 more
europepmc   +1 more source

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

Self‐Assembled Myricetin‐Arginine Conjugate Nanozymes for Targeted Suppression of Joint Inflammation and Osteoclastogenesis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Carrier‐free myricetin‐arginine conjugate nanozymes (MANZs) have been fabricated through a Mannich reaction and spontaneous self‐assembly. MANZs selectively accumulate in inflamed joints by targeting M1 macrophages via CAT2‐mediated uptake. The nanozymes can effectively modulate macrophage polarization, suppress osteoclast differentiation, and mitigate
Jiachang Hong, Penghao Ji, Jinxi An, Junchao Huang, Ziheng Bu, Xudong Zhang, Wei Liu, Tingyu Wu, Sen Wang, Wei Zhu, Yuhui Li, Jixian Wan, Sudan Xu, Minfeng Huo, Peng Wu   +14 more
wiley   +1 more source

Comparative Evaluation of Lipopolysaccharide Administration Methods to Induce Acute Lung Injury in Murine Models: Efficacy, Consistency, and Technical Considerations. [PDF]

Crit Care Explor
Kuhar E, Stewart DJ, Engelberts D, Jahandideh F, Jeffers MS, Khang J, Zhang H, Kristof AS, Thébaud B, Vadivel A, Fergusson DA, Lalu MM.   +11 more
europepmc   +1 more source

Pearl‐Like Bioinspired Coating Enables Regulation of Mg Degradation for Osteoporotic Bone Repair

Advanced Science, EarlyView.
In this study, inspired by pearl architecture, we developed a layered Ca–P “brick” and Fn‐mimetic peptide “mortar” coating on Mg alloys. The Ca–P layer moderates corrosion and offers mineral cues, while the peptide enhances adhesion and regulates immune‐vascular responses.
Siming Zhang, Tao Zhang, Yuan Chen, Nikolaos Kourkoumelis, Mo Chen, Jiale Dong, Zhenyu Li, Yanling Zhou, Ning Li, Chen Zhu, Xifu Shang, Jiaxiang Bai, Xianzuo Zhang   +12 more
wiley   +1 more source

Effect of dietary natural phytoncide on blood characteristics to lipopolysaccharide challenge of Hanwoo cattle. [PDF]

J Anim Sci Technol
Park B, Kang D, Jang S, Kim U, Kim J, Choi B, Kim S, Chung K.   +7 more
europepmc   +1 more source

Prenatal lipopolysaccharide exposure programs the early-life lung development by modulating mesenchymal fibroblasts in a time- and dose-dependent manner. [PDF]

BMC Med
Dong Y, Hadzic S, Leidner A, Marega M, Procida-Kowalski T, Bartkuhn M, Rivetti S, Ehrhardt H, Bellusci S.   +8 more
europepmc   +1 more source

The Concentration and Duration of Lipopolysaccharide Stimulation Produce Different Cytokine Responses in an Ex Vivo Whole Blood Model in Horses. [PDF]

Vet Sci
Mitlyng N, Hobbs KJ, Cooper BL, Sheats MK.   +3 more
europepmc   +1 more source

Serum Zonulin and Lipopolysaccharide (LPS) Levels in Early Myocardial Infarction: Association with Left Ventricular Ejection Fraction. [PDF]

J Clin Med
Olędzki S, Kukowka A, Siennicka A, Jakubiak N, Maciejewska-Markiewicz D, Kiedrowicz R, Kaźmierczak J.   +6 more
europepmc   +1 more source