Results 321 to 330 of about 640,235 (385)

Melanocortin Receptor-Mediated Anti-Inflammatory Effect of Acthar® Gel in Human Myeloid Cells.

Neuroimmunomodulation
Hayes K, Wright D.
europepmc   +1 more source

A randomized placebo-controlled trial in healthy volunteers examining the effects of acetaminophen and NO-acetaminophen NCX 701 in human endotoxemia. [PDF]

Sci Rep
Brunner-Ziegler S, Staudacher M, Schörgenhofer C, Strasser-Marsik C, Derhaschnig U, Mayr FB, Steiner S, Jilma B.   +7 more
europepmc   +1 more source

An Effective Oral Drug Delivery Route for Pharmacokinetic Complications: Spirulina Lipid Nanotechnology System

Advanced Science, EarlyView.
Spirulina‐nano system facilitates the formation of drug coating on spirulina's surface through electrostatic adsorption. It targets intestinal villi effectively and overcomes the pharmacokinetic complications of IBS‐D. This system successfully carried out the treatment of multiple symptoms, including diarrhea, visceral hypersensitivity, mental symptoms,
Jiahui Ye, Xinyi Wu, Jin Liu, Yongmi Guo, Chong Ji, Zhouyue Wang, Di Yang, Min Zhou   +7 more
wiley   +1 more source

Assessment of intestinal barrier integrity and associations with innate immune activation and metabolic syndrome in acutely ill, antipsychotic-free schizophrenia patients. [PDF]

J Neuroinflammation
Mukherjee K, Guest PC, Nussbaumer M, Dudeck L, Shokati Asl L, Meyer-Lotz G, Dobrowolny H, Borucki K, Bernstein HG, Link A, Relja B, Schiltz K, Nickl-Jockschat T, Steiner J.   +13 more
europepmc   +1 more source

Identification of a Pair of Linear or Cyclic Naturally Inspired Bifunctional Lipopeptide Antibiotics That Overcome Antimicrobial Resistance

Advanced Science, EarlyView.
The underexplored bacterial genus Aquimarina harbors a large biosynthetic potential for discovering new antibiotics. Here, the authors identify a pair of linear or cyclic bifunctional cationic lipopeptide antibiotics, aquicidine L and C4, inspired by the aquicidine gene cluster from Aquimarina.
Lei Li, Yiwen Zhou, Yuzhu Wu
wiley   +1 more source

D-Chiro-Inositol and LPS Induce a PCOS-Like Hyperandrogenic Response in Human KGN Granulosa Cells. [PDF]

J Cell Mol Med
Giuliani C, Casoli G, Di Emidio G, Tatone C, Bevilacqua A.   +4 more
europepmc   +1 more source

Inhibition of Macrophage ARID3A Alleviates Myocardial Ischemia‐Reperfusion Injury After Heart Transplantation by Reducing THBS1/CD47 Signaling‐Mediated Neutrophil Extracellular Traps Formation

Advanced Science, EarlyView.
This study reveals that ARID3A in macrophages can transcriptionally regulate the THBS1‐CD47 axis after heart transplantation (HT), thereby inducing activated neutrophils to release NETs through the p38 MAPK signaling pathway. The itaconate derivative 4‐OI can inhibit ARID3A in macrophages and promote the accumulation of antioxidant factors, thereby ...
Hao Tian, Yonghong Xiong, Junbiao Zhan, Zhikun Lu, Yuxi Zhang, Yan Leng, Qin Huang, Zhongyuan Xia   +7 more
wiley   +1 more source

Absence of lipopolysaccharide (LPS) expression in breast cancer cells. [PDF]

Cell Oncol (Dordr)
de Miranda NFCC, Smit VTHBM, van der Ploeg M, Wesseling J, Neefjes J.   +4 more
europepmc   +1 more source

Interfacial Coordination‐Engineered Emulgel Modulates the Osteo‐Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway‐Induced Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of HIPPE‐QU‐mediated periodontal regeneration. a) Fabrication process and microstructure of HIPPE‐QU. b) Antimicrobial and immunomodulatory HIPPE‐QU hydrogel for periodontal regeneration. HIPPE‐QU hydrogel co‐delivers HA‐Cu, GNPs, and QU, providing antimicrobial effects and reprogramming the immune microenvironment to promote ...
Hui Zhang, Xiao Huang, Rui Chen, Weimin Lin, Linke Li, Xi Peng, Xinxi Yang, Xingyu Chen, Tailin Guo, Jie Weng, Jianshu Li, Quan Yuan, Huan Tan, Mengyuan Wang   +13 more
wiley   +1 more source