Results 331 to 340 of about 640,235 (385)

Effects of Short-Term Calcifediol Supplementation on Leukocyte Cytokine Production in Healthy Dogs: A Randomized, Double-Blinded, Placebo-Controlled Crossover Trial. [PDF]

J Vet Intern Med
Jaffey JA, Kreisler R, Backus RC, Gordon D, Chittick L.   +4 more
europepmc   +1 more source

A Sensitive Ratiometric Thermometer Constructed by AIEgen‐Based Mixed Lanthanide MOF for Intracellular Temperature Mapping

Advanced Science, EarlyView.
Temperature is a crucial fundamental physical parameter involved in all life activities. An AIEgen‐based mixed lanthanide MOF is synthesized. In the physiological temperature range, this MOF shows superior performance. To achieve the detection of intracellular temperature, a nanoscale mixed LnMOF is synthesized and further modified to enable the visual
Zhijia Li, Jieping Zhang, Zhiyuan Wu, Hang Lei, Yunfang Zhao, Wenqiu Qi, Xue Gao, Feilong Jiang, Yongsheng Liu, Lian Chen, Maochun Hong   +10 more
wiley   +1 more source

The double-edged nature of trained immunity. [PDF]

Elife
Leopold Wager CM, Schlesinger LS.
europepmc   +1 more source

Hepatocyte‐Specific GSDMD Deficiency Aggravates Sepsis by Disrupting Non‐Canonical Secretion of Anti‐Inflammatory Factors

Advanced Science, EarlyView.
This study proposes for the first time that hepatic GSDMD plays a key protective role in sepsis. Hepatic GSDMD may release inflammatory inhibitory factors including VEGF‐B and Gremlin‐1 through pore‐forming activity to inhibit the production of inflammatory factors from macrophages, thereby alleviating the inflammatory response of septic mice ...
Yihan Qian, Bingrui Wang, Chang Yu, Yuge Zhou, Weifan Huang, Xing Rong, Yali Sang, Jiangang Song, Hailong Wu, Xiaoni Kong   +9 more
wiley   +1 more source

Strategic Timing of Gene Silencing: Cellular Kinetics‐Based Administration of siRNA for Optimized Photothermal Cancer Treatment

Advanced Science, EarlyView.
Coordinating therapy with gene expression kinetics emerges as a key strategy for maximizing nanomedicine efficacy in aggressive cancers. A hybrid nanocarrier delivering HSP70‐targeting siRNA demonstrates this chronotherapeutic principle through systematic cellular profiling.
Tianliang Fang, Li Li, Ziyad Tariq Muhseen, Lucas A. Lane, Huiming Cai, Christopher J. Butch, Yiqing Wang   +6 more
wiley   +1 more source

Cytokine dysregulation in children with severe neurological impairment correlates with significant clinical outcomes. [PDF]

Front Pediatr
Allen J, Isaza-Correa J, Kelly L, Melo A, Power C, Mahony A, McDonald D, Molloy EJ.   +7 more
europepmc   +1 more source

Virulence‐Selective Trap–Capture–Kill Antibacterial Nanostructures With Immune–Metabolic Regulation for Treating Implant‐Associated Infections

Advanced Science, EarlyView.
A virulence‐selective antibacterial system based on fascaplysin derivative 14‐modified TiO2 nanostructure (F‐14‐TNA) is developed for treating implant‐associated infections. F‐14‐TNA selectively traps hyperpathogenic bacteria via chemotaxis, captures them electrostatically, and kills them via reactive oxygen species‐mediated pathways.
Xiaodong Hu, Jiaqi Zhong, Yujiong Chen, Botao Liu, Tianyu Du, Weilai Zhu, Minzhe Zheng, Hongze Liang, Jiahua Ni, Zhaoxiang Peng   +9 more
wiley   +1 more source

Jianpi Yifei Tongluo recipe attenuates inflammation by promoting the expression of interferon regulatory factor 4 in the rat model of chronic obstructive pulmonary disease. [PDF]

J Tradit Chin Med
Wei W, Qi L, Ling FU, Haiqiao WU.
europepmc   +1 more source

Loss-of-function of lipopolysaccharide-responsive beige-like anchor protein causes inflammatory bowel disease-a case report and literature review. [PDF]

Transl Pediatr
Wang Z, Fang Y, Yu J, Chen J, Luo Y.
europepmc   +1 more source

Gut Microbiota Mediator Level and Its Relation to Disease Activity in Ankylosing Spondylitis. [PDF]

Arch Rheumatol
Nasrallah H, Altındağ Ö, Akaltun MS, Bozdayı MA, Örkmez M, Balbal E, Gür A.   +6 more
europepmc   +1 more source