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A Journey from Structure to Function of Bacterial Lipopolysaccharides.
Chemical Reviews, 2021Lipopolysaccharide (LPS) is a crucial constituent of the outer membrane of most Gram-negative bacteria, playing a fundamental role in the protection of bacteria from environmental stress factors, in drug resistance, in pathogenesis, and in symbiosis ...
F. Di Lorenzo +5 more
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LIPOPOLYSACCHARIDE RECOGNITION, CD14, AND LIPOPOLYSACCHARIDE RECEPTORS
Infectious Disease Clinics of North America, 1999The ability of a host to sense invasion by a pathogenic organism, and to respond appropriately to control infection, is paramount to survival. To that end, an array of receptors and binding proteins has evolved as part of the innate immune system to detect Gram-negative bacteria.
R R, Ingalls +4 more
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Journal of Leukocyte Biology, 1991
Abstract The present study demonstrates that with time in culture blood monocytes (MO) lose their ability to express procoagulant activity (PCA) and secrete tumor necrosis factor-alpha (TNFα) in culture medium in response to lipopolysaccharide (LPS) stimulation.
A Y, Annenkov, F S, Baranova
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Abstract The present study demonstrates that with time in culture blood monocytes (MO) lose their ability to express procoagulant activity (PCA) and secrete tumor necrosis factor-alpha (TNFα) in culture medium in response to lipopolysaccharide (LPS) stimulation.
A Y, Annenkov, F S, Baranova
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Increased Liver Localization of Lipopolysaccharides in Human and Experimental NAFLD
Hepatology, 2019Lipopolysaccharides (LPS) is increased in nonalcoholic fatty liver disease (NAFLD), but its relationship with liver inflammation is not defined.
G. Carpino +15 more
semanticscholar +1 more source
Supported Lipopolysaccharide Bilayers
Langmuir, 2012In this report, the formation of supported lipopolysaccharide bilayers (LPS-SLBs) is studied with extracted native and glycoengineered LPS from Escherichia coli ( E. coli ) and Salmonella enterica sv typhimurium ( S. typhimurium ) to assemble a platform that allows measurement of LPS membrane structure and the detection of membrane tethered ...
Stefan, Kaufmann +6 more
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Lipopolysaccharides ofShigella sonnei
Applied Biochemistry and Microbiology, 2000Immunobiological properties of native lipopolysaccharides (LPS) from virulent and avirulent strains of Shigella sonnei bacteria (LPS-V and LPS-A, respectively) were studied. In avirulent bacteria, LPS-V induced immunosuppressive activity specific of the virulent strain. LPS of the avirulent strain, whereas LPS-A lacked this property.
E V, Borisova, V A, Borisov
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PATHOBIOLOGY OF LIPOPOLYSACCHARIDE
Journal of Toxicology and Environmental Health, 1997Lipopolysaccharide is a component of the gram-negative bacterial cell wall that is responsible for 25,000-50,000 deaths in the United States each year. The sequelae of gram-negative infection and septicemia leading to death include fever, hypotension with inadequate tissue perfusion, and disseminated intravascular coagulation.
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Antibodies to lipopolysaccharide
Journal of Immunological Methods, 1995Lipopolysaccharides (LPS) are indispensable structural components of the Gram-negative bacterial outer membrane and are major determinants of virulence in pathogenic species. In the infected host LPS is better known as endotoxin where it acts as a potent stimulator of the inflammatory response.
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