Results 291 to 300 of about 164,679 (343)

Autoantibodies to granulocytes in chronic inflammatory bowel disease are not correlated with antibodies to intestinal goblet cells in ulcerative colitis and to pancreatic juice in Crohn`s disease [PDF]

, 1992
Brühmann, A., Müller-Kunert, E., Olbrich, S., Schlumberger, W., Scriba, Peter Christian, Stöcker, W.   +5 more
core  

Interfacial Coordination‐Engineered Emulgel Modulates the Osteo‐Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway‐Induced Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of HIPPE‐QU‐mediated periodontal regeneration. a) Fabrication process and microstructure of HIPPE‐QU. b) Antimicrobial and immunomodulatory HIPPE‐QU hydrogel for periodontal regeneration. HIPPE‐QU hydrogel co‐delivers HA‐Cu, GNPs, and QU, providing antimicrobial effects and reprogramming the immune microenvironment to promote ...
Hui Zhang, Xiao Huang, Rui Chen, Weimin Lin, Linke Li, Xi Peng, Xinxi Yang, Xingyu Chen, Tailin Guo, Jie Weng, Jianshu Li, Quan Yuan, Huan Tan, Mengyuan Wang   +13 more
wiley   +1 more source

Ghrelin improves small intestinal barrier damage in sepsis by promoting miR-143/ATG2B-mediated autophagy. [PDF]

PLoS One
Liu J, Shi K, Cai H, Zheng Z, Fan B, Yang X, Shao Z.   +6 more
europepmc   +1 more source

A Sensitive Ratiometric Thermometer Constructed by AIEgen‐Based Mixed Lanthanide MOF for Intracellular Temperature Mapping

Advanced Science, EarlyView.
Temperature is a crucial fundamental physical parameter involved in all life activities. An AIEgen‐based mixed lanthanide MOF is synthesized. In the physiological temperature range, this MOF shows superior performance. To achieve the detection of intracellular temperature, a nanoscale mixed LnMOF is synthesized and further modified to enable the visual
Zhijia Li, Jieping Zhang, Zhiyuan Wu, Hang Lei, Yunfang Zhao, Wenqiu Qi, Xue Gao, Feilong Jiang, Yongsheng Liu, Lian Chen, Maochun Hong   +10 more
wiley   +1 more source

Revealing the molecular mechanisms underlying Xuebijing against sepsis and septic acute kidney injury via bioinformatics and experimental approaches. [PDF]

PLoS One
Li X, Ren K, Baran MR, Tang J, Wang L, Tchivelekete GM, Guo Y, Bai Y, Yan W, Shu X.   +9 more
europepmc   +1 more source

Hepatocyte‐Specific GSDMD Deficiency Aggravates Sepsis by Disrupting Non‐Canonical Secretion of Anti‐Inflammatory Factors

Advanced Science, EarlyView.
This study proposes for the first time that hepatic GSDMD plays a key protective role in sepsis. Hepatic GSDMD may release inflammatory inhibitory factors including VEGF‐B and Gremlin‐1 through pore‐forming activity to inhibit the production of inflammatory factors from macrophages, thereby alleviating the inflammatory response of septic mice ...
Yihan Qian, Bingrui Wang, Chang Yu, Yuge Zhou, Weifan Huang, Xing Rong, Yali Sang, Jiangang Song, Hailong Wu, Xiaoni Kong   +9 more
wiley   +1 more source

TLR2-induced surface mobilization and release of CD14 in human platelets. [PDF]

Sci Rep
Kobsar A, Vaz DS, Zeller-Hahn J, Koessler A, Weber K, Kuhn S, Stigloher C, Koessler J.   +7 more
europepmc   +1 more source

Strategic Timing of Gene Silencing: Cellular Kinetics‐Based Administration of siRNA for Optimized Photothermal Cancer Treatment

Advanced Science, EarlyView.
Coordinating therapy with gene expression kinetics emerges as a key strategy for maximizing nanomedicine efficacy in aggressive cancers. A hybrid nanocarrier delivering HSP70‐targeting siRNA demonstrates this chronotherapeutic principle through systematic cellular profiling.
Tianliang Fang, Li Li, Ziyad Tariq Muhseen, Lucas A. Lane, Huiming Cai, Christopher J. Butch, Yiqing Wang   +6 more
wiley   +1 more source

The effect of microbial metabolites from colonic protein fermentation on bacteria-induced cytokine production in dendritic cells. [PDF]

Biofactors
Xie Z, Eriksen DB, Johnsen PR, Nielsen DS, Frøkiær H.   +4 more
europepmc   +1 more source

Virulence‐Selective Trap–Capture–Kill Antibacterial Nanostructures With Immune–Metabolic Regulation for Treating Implant‐Associated Infections

Advanced Science, EarlyView.
A virulence‐selective antibacterial system based on fascaplysin derivative 14‐modified TiO2 nanostructure (F‐14‐TNA) is developed for treating implant‐associated infections. F‐14‐TNA selectively traps hyperpathogenic bacteria via chemotaxis, captures them electrostatically, and kills them via reactive oxygen species‐mediated pathways.
Xiaodong Hu, Jiaqi Zhong, Yujiong Chen, Botao Liu, Tianyu Du, Weilai Zhu, Minzhe Zheng, Hongze Liang, Jiahua Ni, Zhaoxiang Peng   +9 more
wiley   +1 more source