Results 121 to 130 of about 739,667 (342)

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

Advanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac, Luv Patel, Nguyen Tran, Amarnath Singam, DongSoo Yun, Prasun Guha, Seungman Park, Chandrabali Bhattacharya   +7 more
wiley   +1 more source

Apoprotein(a) isoforms and plasma LP(a) concentration in members of four families [PDF]

Journal of Medical Biochemistry, 2008
Apoprotein(a) is a multikringle protein which shows a genetically inherited size polymorphism. The APO(a) gene is located at the telomeric region of chromosome 6q2.6-q 2.7. Apo(a) size polymorphism is a major determinant of Lp(a) levels.
Labudovik Danica, Tosheska Katerina, Alabakovska Sonja, Bogdanska Jasna, Todorova Bojana B.   +4 more
doaj  

Lipoproteins in Coronary Artery Disease [PDF]

, 1957

openalex   +1 more source

A Programmable Nanovaccine Platform Based on M13 Bacteriophage for Personalized Cancer Vaccine and Therapy

Advanced Materials, EarlyView.
A reprogrammed (RP) phage‐based nanovaccine platform has been developed that allows single‐step assembly with precise control over adjuvanticity, antigen density, and nanoparticle size. By enhancing TLR9 activation and neoantigen display, this platform enables a potent personalized vaccine targeting tumor‐specific neoantigens. When combined with immune
Shengnan Huang, Yanpu He, Allison Madow, Huaiyao Peng, Mirielle Griffin, Jifa Qi, Mantao Huang, Heather Amoroso, Riley Abrashoff, Nimrod Heldman, Angela M. Belcher   +10 more
wiley   +1 more source

Association of Butyryl Cholinesterase and Recurrent Ischemic Stroke: A Cross-Sectional Study

International Journal of General Medicine
Ruomeng Chen,1,2 Kun Zhang,1,2 Hui Liu,1,2 Lijuan Liu,1,2 Hui Li,3 Yan Yan,1,2 Zhou Zhou,1,2 Chaoyue Meng,1,2 Xuelin Wang,4 Haoran Wu,4 Ruihan Miao,4 Rui Wang,1,2 Xiaoyun Liu1,2,4,5 1Department of Neurology, The First Hospital of Hebei Medical University,
Chen R, Zhang K, Liu H, Liu L, Li H, Yan Y, Zhou Z, Meng C, Wang X, Wu H, Miao R, Wang R, Liu X   +12 more
doaj  

Measuring Lp(a) particles with a novel isoform-insensitive immunoassay illustrates efficacy of muvalaplin

Journal of Lipid Research
Lipoprotein(a) [Lp(a)] is a cardiovascular risk factor, and there is considerable interest in developing Lp(a)-lowering therapeutics for cardiovascular prevention.
Craig A. Swearingen, John H. Sloan, Grace M. Rhodes, Robert W. Siegel, Nico Bivi, Yuewei Qian, Robert J. Konrad, Michael Boffa, Marlys Koschinsky, John Krege, Giacomo Ruotolo, Stephen J. Nicholls, Laura F. Michael, Yi Wen   +13 more
doaj   +1 more source

An Investigation of Serum Lipids and Lipoproteins by Paper Electrophoresis [PDF]

, 1955
W. G. Dangerfield, ElspethB. Smith
openalex   +1 more source

Correlative Super‐Resolution Imaging of Cellular Nanopores Facilitated by Transparent Polymer Waveguide Chips

Advanced Optical Materials, Volume 13, Issue 8, March 13, 2025.
Correlative super‐resolution optical imaging of the ultrastructure of rat liver sinusoidal endothelial cells (LSECs) across a large field of view (FOV) with 3D structured illumination microscopy (3D‐SIM) and single‐molecule localization microscopy (SMLM), facilitated by a transparent polymer photonic waveguide chip, is presented.
Surjendu Bikash Dutta, Jasmin Celine Schürstedt‐Seher, Anders Kokkvoll Engdahl, Wolfgang Hübner, Stefan Belle, Karolina Szafranska, Peter McCourt, Ralf Hellmann, Mark Schüttpelz, Thomas Huser   +9 more
wiley   +1 more source

Electrophoresis and Monomolecular Layer Studies with Serum Lipoproteins [PDF]

, 1955
D. Adlersberg, Elaine T. Bossak, Irving H. Sher, Harry Sobotka   +3 more
openalex   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source