Results 161 to 170 of about 2,885,946 (243)

Breaking barriers: Smart vaccine platforms for cancer immunomodulation

Cancer Communications, EarlyView.
Abstract Despite significant advancements in cancer treatment, current therapies often fail to completely eradicate malignant cells. This shortfall underscores the urgent need to explore alternative approaches such as cancer vaccines. Leveraging the immune system's natural ability to target and kill cancer cells holds great therapeutic potential ...
Mohammad Mahmoudi Gomari, Taha Ghantabpour, Nima Pourgholam, Neda Rostami, Stephen M. Hatfield, Farzaneh Namazifar, Shadi Abkhiz, Seyed Sadegh Eslami, Mahsa Ramezanpour, Mahsa Darestanifarahani, Igor Astsaturov, Sidi A. Bencherif    +11 more
wiley   +1 more source

Elevated Lipoprotein(a) Is Common in People With Familial Hypercholesterolemia and Negative Genetic Screening. [PDF]

JACC Adv
Gainsborough F, Welsh P, Sattar N, Panarelli M.   +3 more
europepmc   +1 more source

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

Cancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu   +11 more
wiley   +1 more source

Lipoprotein (a) Distribution in Aortic Stenosis Patients: Are Lp(a) Reducing Agents the Ultimate Solution? [PDF]

JACC Adv
Durr MR, Burwash IG, Lau L, Alfraidi H, Mulloy A, Tavosi A, Arangalage D, Chan V, Lakhani M, Aljamaan A, Prosperi-Porta G, Gauda R, Beauchesne L, Mesana T, Messika-Zeitoun D.   +14 more
europepmc   +1 more source

Combating cancer immunotherapy resistance: a nano‐medicine perspective

Cancer Communications, EarlyView.
Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong, Xintong Xie, Juan Wu, Xiangyu Wang, Wenxiang Zhang, Shuowen Wang, Daria Valerievna Abbasova, Yi Fang, Hongnan Jiang, Jidong Gao, Jing Wang   +10 more
wiley   +1 more source

Strong association between atherogenic index of plasma and obesity in college students. [PDF]

BMC Endocr Disord
Wang ZL, Li J, Sun CH, Yin X, Zhi XY, Liu YT, Zheng YY, Wu TT, Xie X.   +8 more
europepmc   +1 more source

Lipoprotein subclasses and gastrointestinal cancers: novel perspectives and potential associations. [PDF]

Front Nutr
Yang C, Liu D, Wang Y, Cao F.
europepmc   +1 more source

LC‐DAD‐MSn and HR‐LC‐QTOF analysis of Ziziphus budhensis leaves and evaluation of their in vitro and in vivo biological activities

Chemistry &Biodiversity, Accepted Article.
Ziziphus budhensis is a species described in 2015 in Nepal poorly studied for its phytochemical composition and possible bioactivities. In this study, six extracts were obtained from Z. budhensis leaves using ultrasound assisted extraction with solvents in increasing polarity.
Samjhana Bharati, Binita Maharjan, Timila Shrestha, Shyam Sharan Shrestha, Stefania Sut, Hari Prasad Devkota, Ram Lal Swagat Shrestha, Stefano Dall'Acqua   +7 more
wiley   +1 more source

Association of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and chronic kidney disease in elderly insights from NHANES. [PDF]

Sci Rep
Sun Y, Li Z, Feng N.
europepmc   +1 more source

Structural, Spectroscopic, and Docking Analysis of N,O‐Donor Ligand Metal Complex Nanoparticles With Hypolipidemic Effects via Lipoprotein Lipase Activation in High‐Fat Diet Mice

Chemistry &Biodiversity, EarlyView.
Hypolipidemic influence of CETZ.2HCl‐(H1‐antihistamine) metal‐complexes on “C57Bl/6‐mice” fed high‐fat‐diet. ABSTRACT New Cd(II), Zn(II), and Cu(II) chelates with cetirizine.2HCl (CETZ.2HCl) in incidence of 1,10 phenanthroline monohydrate (Phen.H2O) were synthesized in search of new biologically active compounds.
Sherif M. Abd El‐Hamid, Safa W. Aziz, Amira A. Mohamed, Mohammed S. El‐Gedamy, Ahmed E. Salem, Soha F. Mohammed, Wael A. Zordok, Adriano Sofo, Mohamed A. Sabry, Sadeek A. Sadeek, Hazem S. Elshafie   +10 more
wiley   +1 more source