Results 221 to 230 of about 739,667 (342)

Neurophilic Biomimetic Lipoprotein‐Mediated Targeted Nerve Growth Factor Delivery for Traumatic Brain Injury Therapy

open access: yesAdvanced Science, EarlyView.
Design of neurophilic biomimetic lipoprotein for intracerebral delivery of nerve growth factor (NGF) to traumatic brain injury (TBI). Nc‐rHDL@P can cross the BBB through ApoE3‐receptors interaction and target neurons via αRDP‐nAChR interaction. Nc‐rHDL@P delivers NGF to the lesion sites, rescues neurons, curbs inflammation, boosts sensorimotor and ...
Jialin Huang   +21 more
wiley   +1 more source

Hologenomics Reveals Specialized Dietary Adaptations in the Mengla Snail‐Eating Snake

open access: yesAdvanced Science, EarlyView.
Dietary adaptation studies from a holobiome perspective are scarce beyond mammals. This research reveals how genomic and microbial interactions drive dietary specialization in the Mengla snail‐eating snake, with evidence of gut symbiont convergence between reptiles and mammals.
Chaochao Yan   +10 more
wiley   +1 more source

Efficacy and safety of PCSK9 inhibitors in patients with chronic kidney disease. [PDF]

open access: yesBMC Nephrol
Tang H   +6 more
europepmc   +1 more source

Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review

open access: yesAdvanced Science, EarlyView.
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu   +7 more
wiley   +1 more source

Influence of Lipoprotein on the Freezing of Bovine Spermatozoa

open access: bronze, 1957
G. Bialy   +3 more
openalex   +1 more source

Inhaling Eugenol Inhibits NAFLD by Activating the Hepatic Ectopic Olfactory Receptor Olfr544 and Modulating the Gut Microbiota

open access: yesAdvanced Science, EarlyView.
Inhalable eugenol (EUG) from clove oil attenuates NAFLD by activating hepatic olfactory receptor Olfr544, triggering cAMP/PKA/CREB signaling to enhance lipolysis/oxidation. EUG concurrently restores gut microbiota, enriching probiotics (L. reuteri XR23/L. johnsonii XR25) and metabolites (IPA/5‐HIAA) that suppress lipogenesis.
Xiao‐Ran Wang   +15 more
wiley   +1 more source

Hepatic Lipoprotein Metabolism: Current and Future In Vitro Cell-Based Systems. [PDF]

open access: yesBiomolecules
Kiss I   +5 more
europepmc   +1 more source

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