Results 81 to 90 of about 2,885,946 (243)

Lipoprotein (a) Testing in Patients With Atherosclerotic Cardiovascular Disease in 5 Large US Health Systems

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Lipoprotein (a) is an independent risk factor for atherosclerotic cardiovascular disease. However, lipoprotein (a) testing remains variable and it is unclear what factors influence testing and if testing changes clinical management.
Nishant P. Shah, Hillary Mulder, Elizabeth Lydon, Karen Chiswell, Xingdi Hu, Zachary Lampron, Lauren Cohen, Manesh R. Patel, Susan Taubes, Wenliang Song, Suresh R. Mulukutla, Anum Saeed, Daniel P. Morin, Steven M. Bradley, Adrian F. Hernandez, Neha J. Pagidipati   +15 more
doaj   +1 more source

Elevated Lp(a) Levels Correlate with Severe and Multiple Coronary Artery Stenotic Lesions

Vascular Health and Risk Management, 2023
Cynthia Al Hageh,1,* Stephanie Chacar,1,2,* Michella Ghassibe-Sabbagh,3 Daniel E Platt,4 Andreas Henschel,5 Hamdan Hamdan,1,2 Dominique Gauguier,6,7 Yara El Murr,3 Eman Alefishat,8,9 Elie Chammas,10 Siobhán O’Sullivan,1 Antoine Abchee,11 ...
Al Hageh C, Chacar S, Ghassibe-Sabbagh M, Platt DE, Henschel A, Hamdan H, Gauguier D, El Murr Y, Alefishat E, Chammas E, O'Sullivan S, Abchee A, Nader M, Zalloua PA   +13 more
doaj  

Effect of Nandrolone Decanoate on Serum Lipoprotein (a) and its isoforms in hemodialysis patients

Lipids in Health and Disease, 2004
Malnutrition, anemia and increased atherosclerosis are the main causes of mortality in hemodialysis patients. Therapies designed to improve the disorders might therefore be expected to improve outcome.
Rohbaninoubar Mohammad, Argani Hassan, Ghorbanihaghjo Amir, Rashtchizadeh Nadereh   +3 more
doaj   +1 more source

Homocysteine Promotes the Pathogenesis of Atherosclerosis through the Circ‐PIAS1‐5/miR‐219a‐2‐3p/TEAD1 Axis

Advanced Science, EarlyView.
A model is schematically represented for the major molecular mechanisms by which homocysteine (Hcy) accelerates the nuclear export of circ‐PIAS1‐5, which regulates atherosclerosis by acting as a competing endogenous RNA for miR‐219a‐2‐3p. Hcy enrichment of circ‐PIAS1‐5 leads to YTHDC1 binding to circ‐PIAS1‐5 and promotes its intracellular localization ...
Shengchao Ma, Fei Ma, Ning Ding, Lin Xie, Anning Yang, Jiangyong Shen, Yun jiao, Kai Wu, YueE Chai, Zhigang Bai, Jiantuan Xiong, Nan Li, Huiping Zhang, Yideng Jiang   +13 more
wiley   +1 more source

The roles of MMP8/MMP10 polymorphisms in ischemic stroke susceptibility

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Background Ischemic stroke (IS), a multifactorial and polygenic disease, is the most common cause of death. This study aimed to determine the roles of MMP8/MMP10 polymorphisms in IS susceptibility in the Chinese Han population. Methods MMP8 rs1940475 and rs3765620, and MMP10 rs17860949 from 700 IS patients and 700 controls were genotyped by ...
Yong Zhao, Qi Zhang, Xiaobo Zhang, Yu Zhang, Ying Lu, Xiaojuan Ma, Weiping Li, Xiaochen Niu, Gejuan Zhang, Mingze Chang, Wenzhen Shi, Ye Tian   +11 more
wiley   +1 more source

Apoprotein(a) isoforms and plasma LP(a) concentration in members of four families [PDF]

Journal of Medical Biochemistry, 2008
Apoprotein(a) is a multikringle protein which shows a genetically inherited size polymorphism. The APO(a) gene is located at the telomeric region of chromosome 6q2.6-q 2.7. Apo(a) size polymorphism is a major determinant of Lp(a) levels.
Labudovik Danica, Tosheska Katerina, Alabakovska Sonja, Bogdanska Jasna, Todorova Bojana B.   +4 more
doaj  

Lipoprotein (a) levels in relation to severity of coronary artery disease in north Indian patients

Heart Views, 2013
Background: Lipoprotein (a) [Lp (a)] is an established risk marker of coronary artery disease which is independent from other risk factors. Objective: The aim was to address the association between Lp (a) and CAD risk in North Indians.
Fauzia Ashfaq, Pravin Kumar Goel, Rishi Sethi, Mohd Idrees Khan, Wahid Ali, Mohd Zafar Idris   +5 more
doaj   +1 more source

Asprosin‐FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development

Advanced Science, EarlyView.
Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu, Min Feng, Yi Chen, Hong‐Lin Jia, Qi Zhang, Ming Tong, Yan‐Xi Li, Yu Zhao, Xin‐Xin Liu, Shi‐Feng Cao, Zheng‐kai Wang, Hou‐wei Li, Xue Liu, Yan Zhang   +13 more
wiley   +1 more source

Lipid metabolism in pancreatic cancer: emerging roles and potential targets

Cancer Communications, Volume 42, Issue 12, Page 1234-1256, December 2022., 2022
Abstract Pancreatic cancer is one of the most serious health issues in developed and developing countries, with a 5‐year overall survival rate currently <9%. Patients typically present with advanced disease due to vague symptoms or lack of screening for early cancer detection.
Xinpeng Yin, Ruiyuan Xu, Jianlu Song, Rexiati Ruze, Yuan Chen, Chengcheng Wang, Qiang Xu   +6 more
wiley   +1 more source

Association of Butyryl Cholinesterase and Recurrent Ischemic Stroke: A Cross-Sectional Study

International Journal of General Medicine
Ruomeng Chen,1,2 Kun Zhang,1,2 Hui Liu,1,2 Lijuan Liu,1,2 Hui Li,3 Yan Yan,1,2 Zhou Zhou,1,2 Chaoyue Meng,1,2 Xuelin Wang,4 Haoran Wu,4 Ruihan Miao,4 Rui Wang,1,2 Xiaoyun Liu1,2,4,5 1Department of Neurology, The First Hospital of Hebei Medical University,
Chen R, Zhang K, Liu H, Liu L, Li H, Yan Y, Zhou Z, Meng C, Wang X, Wu H, Miao R, Wang R, Liu X   +12 more
doaj