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Current Opinion in Lipidology, 2014
Lipoprotein(a) [Lp(a)] is an atherogenic lipoprotein. The metabolism of this lipoprotein is still not well understood.It has long been known that the plasma concentration of Lp(a) is highly heritable, with its genetic determinants located in the apo(a) locus and regulating the rate of hepatic apo(a) production.
Stefania, Lamon-Fava +2 more
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Lipoprotein(a) [Lp(a)] is an atherogenic lipoprotein. The metabolism of this lipoprotein is still not well understood.It has long been known that the plasma concentration of Lp(a) is highly heritable, with its genetic determinants located in the apo(a) locus and regulating the rate of hepatic apo(a) production.
Stefania, Lamon-Fava +2 more
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Biosynthesis and metabolism of lipoprotein (a)
Current Opinion in Lipidology, 1995Significant advances have been made over the past year toward understanding the pathways of lipoprotein (a) biosynthesis and metabolism. Transcriptional and post-translational mechanisms have been identified as important determinants of plasma lipoprotein (a) levels. Assembly of lipoprotein (a) has been shown to be an extracellular event that occurs on
A L, White, R E, Lanford
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Structure and metabolism of lipoprotein (a)
Current Opinion in Lipidology, 1995An understanding of the complex structural and metabolic features of lipoprotein (a) is essential because this lipoprotein particle, with poorly recognized physiological functions, has been implicated in both thrombogenesis and atherogenesis. Studies aimed at investigating the structure-function relationship of apolipoprotein (a) have generated new ...
S M, Marcovina, J D, Morrisett
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Hormonal influences on lipoprotein(a) metabolism
Diabetes, Obesity and Metabolism, 2002link_to_subscribed_fulltext
Pang, RWC, Lam, KSL
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LIPOPROTEIN (A): TREATMENT IN THE METABOLIC CONTEXT
Journal of Hypertension, 2023Objective: Lipoprotein(a) [Lp(a)] is an independent cardiovascular risk factor but is closely associated with other similar risk factors that are manageable with appropriate treatment and guidance. We aimed to study the impact of using combined therapy for managing Lp(a) levels in patients at high cardiovascular risk but ...
Meireles-Brandao Joaquim +3 more
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Low-density lipoprotein triglycerides: A marker for metabolic diseases
Annales de Biologie Clinique, 2023Dyslipidemia plays an essential role in the occurrence and development of cardiovascular diseases, and the regulation of cholesterol and triglyceride metabolism has been applied in the diagnosis, treatment and prognosis of clinical cardiovascular diseases. Following advances in methodology in recent years, low-density lipoprotein triglycerides (LDL-TG)
Xiangxiang, Li, Hao, Shen
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Elastin, a Metabolically Active Lipoprotein
Nature, 1957THE protein elastin has been generally regarded as an inert substance on the basis of its solubility properties1 and tracer studies2 employing carbon-14. That elastic tissue demonstrates dynamic, functional properties other than that of elasticity has been suggested in part by studies on arteriosclerotics. The breakdown of the arterial elastic lamellae
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Understanding the ins and outs of lipoprotein (a) metabolism
Current Opinion in Lipidology, 2022Purpose of review This review summarizes our current understanding of the processes of apolipoprotein(a) secretion, assembly of the Lp(a) particle and removal of Lp(a) from the circulation. We also identify existing knowledge gaps that need to be addressed in future studies. Recent findings
Michael B, Boffa, Marlys L, Koschinsky
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