Results 271 to 280 of about 219,582 (315)
Some of the next articles are maybe not open access.
Lipoprotein (a) is not a metabolic product of other lipoproteins containing apolipoprotein B
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1979125I-Labeled autologous very low density lipoprotein (VLDL) was injected intravenously into three lipoprotein (a) positive individuals. One other lipoprotein (a) positive subject received 125I-labeled VLDL from a a lipoprotein (a) negative donor. Specific activity of apolipoprotein B in VLDL, low density lipoprotein (LDL) and lipoprotein (a) was ...
F, Krempler +3 more
openaire +2 more sources
Recent advances in demystifying the metabolism of lipoprotein(a)
Atherosclerosis, 2022Lipoprotein (a) (Lp(a)) is a strange lipoprotein species causatively independently and significantly associated with cardiovascular diseases and calcified aortic valve stenosis. Elevated plasma Lp(a) levels increase the rate of cardiovascular events at any achieved low-density lipoprotein (LDL) level.
Kévin, Chemello +3 more
openaire +2 more sources
Renal Lipoprotein (a) Metabolism
Journal of Internal Medicine Research & ReportsThe kidney plays a central role in lipoprotein(a) catabolism, acting as a “cemetery for lipoprotein(a)” through uptake, fragmentation, and excretion. Direct human evidence comes from Kronenberg et al., who found significant arteriovenous differences in lipoprotein(a) levels between the aorta and renal vein, demonstrating active renal uptake.
Anita LR Saldanha +3 more
openaire +1 more source
Lipoprotein (a) metabolism estimated by nonsteady‐state kinetics
Lipids, 1999AbstractLipoprotein (a) [Lp(a)] is a low‐density lipoprotein (LDL) particle with an additional apolipoprotein named apo(a). The concentration of Lp(a) in plasma is determined to a large extent by the size of the apo(a) isoform. Because elevated Lp(a) concentrations in plasma are associated with risk for premature coronary heart disease it is important ...
K G, Parhofer +5 more
openaire +2 more sources
Lipoproteins and lipoprotein metabolism
Klinische Wochenschrift, 1983Data now available suggest that a dynamic equilibrium exists in the plasma lipoproteins. Chylomicrons and very low density lipoproteins (VLDL) are primary secretory products of cells and carry triglycerides through the blood stream. As intravascular triglyceride hydrolysis occurs via the action of lipoprotein lipase (LPL), the further metabolism of ...
openaire +2 more sources
The Clinical Investigator, 1994
The mechanisms regulating plasma levels of lipoprotein(a) [Lp(a)] are largely unknown. A two- to three-fold increase in Lp(a) levels in patients with familial hypercholesterolaemia (FH) has implied that LDL receptor activity may be an important factor in determining plasma Lp(a) levels, as it is in determining low-density lipoprotein (LDL) cholesterol ...
G, Lindahl +3 more
openaire +2 more sources
The mechanisms regulating plasma levels of lipoprotein(a) [Lp(a)] are largely unknown. A two- to three-fold increase in Lp(a) levels in patients with familial hypercholesterolaemia (FH) has implied that LDL receptor activity may be an important factor in determining plasma Lp(a) levels, as it is in determining low-density lipoprotein (LDL) cholesterol ...
G, Lindahl +3 more
openaire +2 more sources
Lipoprotein(a): Structure, Metabolism, and Pathophysiology
2013Recent reports on large prospective epidemiological studies strongly suggest that Lp(a) is one of the strongest risk factor for atherosclerosis and myocardial infarction and that the association might be causal. Lp(a) belongs to the cholesterol ester-rich apoB-containing lipoproteins, yet its metabolism is distinct from that of LDL.
Jenkins, Alicia J. +2 more
openaire +2 more sources
Lipoprotein Lp(a): Structure and Metabolism
1989The Lp(a) antigen was first detected in human plasma by Berg [1]. Although initially thought to represent a genetic variant of LDL, it was later shown to be associated with a specific lipoprotein fraction that is now commonly termed Lp(a) (for recent review see [2]).
V. W. Armstrong, H. Kratzin, D. Seidel
openaire +1 more source
Evidence of dependence of lipoprotein(a) on triglyceride and high-density lipoprotein metabolism
Journal of Clinical Lipidology, 2012Lipoprotein(a) [Lp(a)] is a complex lipoprotein consisting of a low-density lipoprotein (LDL)-like ApoB₁₀₀-containing core particle covalently bound to apo(a), a large functionally complex glycoprotein. The mechanisms of Lp(a) metabolism and its interactions with cell-surface lipoprotein receptors are incompletely understood.
Matthew, Konerman +3 more
openaire +2 more sources
[Lipoprotein lipase: a multifunctional enzyme in lipoprotein metabolism].
Presse medicale (Paris, France : 1983), 1996Lipoprotein lipase (LPL) is a rate-limiting enzyme for the hydrolysis of triglycerides. Recently new insights into non-enzymatic functions have emerged. Complete lipoprotein lipase deficiency associated with chylomicronemia is an uncommon (1/10(6) in the general population) autosomal recessive disorder caused by many different lipoprotein lipase gene ...
L, Foubert, P, Benlian, G, Turpin
openaire +1 more source