Results 51 to 60 of about 2,849,839 (287)
Role of Endothelial Cell Lipoprotein Lipase for Brown Adipose Tissue Lipid and Glucose Handling
Frontiers in Physiology, 2022 Cold-induced activation of brown adipose tissue (BAT) has an important impact on systemic lipoprotein metabolism by accelerating the processing of circulating triglyceride-rich lipoproteins (TRL).
Ellen Thiemann +12 more
doaj +1 more source
Global organization of metabolic fluxes in the bacterium, Escherichia coli [PDF]
Nature 427, 839-843 (2004), 2004 Cellular metabolism, the integrated interconversion of thousands of metabolic substrates through enzyme-catalyzed biochemical reactions, is the most investigated complex intercellular web of molecular interactions. While the topological organization of individual reactions into metabolic networks is increasingly well understood, the principles ...
arxiv +1 more source
MicroRNAs and Lipoprotein Metabolism
Journal of Atherosclerosis and Thrombosis, 2014 MicroRNAs(miRNAs; miRs) are small, non-protein-coding RNAs that negatively regulate the gene expression. They bind to specific mRNAs and inhibit translation or promote mRNA degradation. Recently, some miRNAs have been shown to be involved in lipid homoeostasis.
Osamu Baba +6 more
openaire +4 more sources
Sortilin as a Regulator of Lipoprotein Metabolism [PDF]
Current Atherosclerosis Reports, 2012 Elevated low-density lipoprotein cholesterol (LDL-C) is associated with increased risk of atherosclerotic cardiovascular disease (ASCVD) and myocardial infarction (MI). Much of the insight into LDL metabolism has been gained through the study of Mendelian disorders of lipid metabolism.
Daniel J. Rader, Alanna Strong
openaire +3 more sources
IDOL regulates systemic energy balance through control of neuronal VLDLR expression. [PDF]
, 2019 Liver X receptors limit cellular lipid uptake by stimulating the transcription of Inducible Degrader of the LDL Receptor (IDOL), an E3 ubiquitin ligase that targets lipoprotein receptors for degradation.
Ahn, In Sook +29 more
core
, 2004 Apolipoprotein M (apoM) is a 26-kDa protein that is mainly associated with high-density lipoprotein (HDL) in human plasma, with a small proportion present in triglyceride-rich lipoproteins (TGRLP) and low-density lipoproteins (LDL).
Luo, Guanghua +3 more
core +3 more sources
FABP-2 and PPAR-γ Haplotype as Risk Factors for Dyslipidemia in a Type 2 Diabetes Mellitus Population of Santa Rosa del Conlara, San Luis, Argentina [PDF]
, 2014 Introduction: Type 2 Diabetes Mellitus (T2DM) is a complex disorder caused by the interaction between genetic predisposition and environmental factors. Genetics plays an important role on lipid homeostasis. Many genes are involved in the lipid metabolism,
Fernandez, Gustavo +4 more
core +1 more source
Spectral Analysis and Invariant Measure in Studies of the Dynamics of the Hemostasis of a Blood Vessel [PDF]
Ukrainian Journal of Physics, 2021, 66(3), 221A mathematical model of atherosclerosis of a blood vessel is advanced with regard for the entry of low-density lipoproteins (LDLs) into blood. For the first time, the influence of cytokines on the inflammation of a blood vessel at the formation of atherosclerotic plaques is taken into account.
arxiv +1 more source
The Dynamics of Hybrid Metabolic-Genetic Oscillators [PDF]
Chaos. 2013 Mar;23(1):013132, 2013 The synthetic construction of intracellular circuits is frequently hindered by a poor knowledge of appropriate kinetics and precise rate parameters. Here, we use generalized modeling (GM) to study the dynamical behavior of topological models of a family of hybrid metabolic-genetic circuits known as "metabolators." Under mild assumptions on the kinetics,
arxiv +1 more source
Lipid Metabolism and Comparative Genomics [PDF]
, 2006 Unilever asked the Study Group to focus on two problems. The first concerned dysregulated lipid metabolism which is a feature of many diseases including metabolic syndrome, obesity and coronary heart disease.
Jones, Janette +5 more
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