Structured functional regression models for high-dimensional spatial spectroscopy data [PDF]
Modeling and analysis of spectroscopy data is an active area of research with applications to chemistry and biology. This paper focuses on analyzing Raman spectra obtained from a bone fracture healing experiment, although the functional regression model for predicting a scalar response from high-dimensional tensors can be applied to any spectroscopy ...
arxiv
Hemostatic variables in homozygous familial hypercholesterolemia. Effect of regular plasma cholesterol removal by low density lipoprotein apheresis. [PDF]
Giovanni Di Minno+9 more
openalex +1 more source
The giant low-density lipoproteins (LDL) accumulation in the multi-layer artery wall model [PDF]
The mathematical, four-layer model of the LDL transport across the arterial wall including the sensitivity of the transport coefficients to the wall shear stress (WSS) is studied. In that model the advection-diffusion equations in porous media are used to determine the LDL concentration profiles in each layer of the arterial wall.
arxiv
Acute impact of apheresis on oxidized phospholipids in patients with familial hypercholesterolemia1
We measured oxidized phospholipids (OxPL), lipoprotein (a) [Lp(a)], and lipoprotein-associated phospholipase A2 (Lp-PLA2) pre- and postapheresis in 18 patients with familial hypercholesterolemia (FH) and with low(∼10 mg/dl; range 10–11 mg/dl ...
Kiyohito Arai+8 more
doaj
Blood lipoproteins shape the phenotype and lipid content of early atherosclerotic lesion macrophages: a dual-structured mathematical model [PDF]
Macrophages in atherosclerotic lesions exhibit a spectrum of behaviours or phenotypes. The phenotypic distribution of monocyte-derived macrophages (MDMs), its correlation with MDM lipid content, and relation to blood lipoprotein densities are not well understood.
arxiv
Regression Discontinuity Designs: A Decision Theoretic Approach [PDF]
The regression discontinuity design (RDD) is a quasi-experimental design that can be used to identify and estimate the causal effect of a treatment using observational data. In an RDD, a pre-specified rule is used for treatment assignment, whereby a subject is assigned to the treatment (control) group whenever their observed value of a specific ...
arxiv
Effect of Apheresis of Low-Density Lipoprotein on Peripheral Vascular Disease in Hypercholesterolemic Patients with Coronary Artery Disease [PDF]
Abraham A. Kroon
openalex +1 more source
Familial hypercholesterolemia, a genetic disorder marked by elevated low-density lipoprotein cholesterol (LDL-C), poses significant risks for premature atherosclerosis and cardiovascular diseases, particularly during pregnancy. One of the safe methods of
Milos Milincic+6 more
doaj +1 more source
[State of the art: lipoprotein apheresis]. [PDF]
Schatz U, Schettler VJJ, Julius U.
europepmc +1 more source
Bayesian modelling for binary outcomes in the Regression Discontinuity Design [PDF]
The Regression Discontinuity (RD) design is a quasi-experimental design which emulates a randomised study by exploiting situations where treatment is assigned according to a continuous variable as is common in many drug treatment guidelines. The RD design literature focuses principally on continuous outcomes.
arxiv