Results 101 to 110 of about 462,380 (329)

Polyacrylate adsorbents for the selective adsorption of cholesterol-rich lipoproteins from plasma or blood

GMS German Medical Science, 2011
Polyacrylate (PAA) adsorbents selectively bind low density lipoproteins (LDL) from human plasma and blood, whereas very low density lipoproteins (VLDL) are only minimally adsorbed.
Heuck, Claus-Chr.
doaj  

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

Characterization of plasma lipoproteins of grain- and cholesterol-fed White Carneau and Show Racer pigeons.

Journal of Lipid Research, 1985
Plasma cholesterol concentrations from White Carneau (WC) and Show Racer (SR) pigeons consuming a cholesterol-free grain diet averaged about 300 mg/dl, approximately 200 mg/dl as high density lipoproteins (HDL) and the remainder as low density ...
H A Barakat, R W St Clair
doaj   +1 more source

Diets containing sea cucumber (Isostichopus badionotus) meals are hypocholesterolemic in young rats [PDF]

, 2013
Peer reviewedPublisher ...
A Venkateswaran, Alberto Davalos, AO Odegaard, AS Greenberg, AV Khera, BA Janowski, C Zetina Moguel, CD Mathers, DE Kleiner, DJ Gordon, DP Mertz, ER Mojica, FR Van der Leij, G Grant, George Grant, GJ Miller, H Komano, H Leontowicz, HA Tyroler, HH Liu, Hirian Alonso Moshe Barrera-Perez, I Hawa, J Ayo, J Folch, J Lin, J Wen, JC Cohen, JC Cohen, JC Yoon, JD Horton, Jean-Marc A Lobaccaro, JJ Repa, Jorge Montero, Jorge Rubio-Piña, JR Schultz, JW Heinecke, JY Chiang, K Liu, KJ Livak, L Olivera, Leticia Olivera-Castillo, M Yahyavi, MC Damiani, MD Säemann, ME Rodríguez, MF Lopes-Virella, Miguel Angel Olvera-Novoa, N Hasegawa, N Torres, NE Miller, Nina Valadez-Gonzalez, P Araujo, P Lefebvre, Pablo Acereto-Escoffie, RG Herrmann, RK Semple, Roche Diagnostics, Rossanna Rodriguez-Canul, RR Sokal, S Acton, S Najwa, T Park, T Rajamohan, T Sugawara, VL Roger, Víctor Ceja-Moreno, X Duan, X Hu, XQ Hu, XQ Hu, Y Zhong, Yasser Chim-Chi, Z Hossain   +72 more
core   +4 more sources

APOE‐stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease

Advanced Science, EarlyView.
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li, Yike Chen, Daniel Western, Muhammad Ali, Menghan Liu, Katherine Gong, Ying Xu, Joseph Lowery, David M. Holtzman, Chloe Robins, John D. Eicher, Yen‐Ning Huang, ShiWei Liu, Tamina Park, Andrew J. Saykin, Kwangsik Nho, Mahdi Moqri, Richard C. Mohs, Amelia Farinas, Patricia Moran‐Losada, Hamilton Se‐Hwee Oh, Tony Wyss‐Coray, Carlos Cruchaga   +22 more
wiley   +1 more source

Antisense inhibition of apoB synthesis with mipomersen reduces plasma apoC-III and apoC-III-containing lipoproteins

Journal of Lipid Research, 2012
Mipomersen, an antisense oligonucleotide that reduces hepatic production of apoB, has been shown in phase 2 studies to decrease plasma apoB, LDL cholesterol (LDL-C), and triglycerides.
Jeremy D. Furtado, Mark K. Wedel, Frank M. Sacks   +2 more
doaj   +1 more source

Association between skeletal muscle mass and serum concentrations of lipoprotein lipase, GPIHBP1, and hepatic triglyceride lipase in young Japanese men [PDF]

, 2019
学位記番号 ...
Matsumoto, Ryutaro, マツモト, リュウタロウ, 松本, 隆太郎   +2 more
core  

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

Advanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du, Zetao Dang, Baofeng Xu, Jiajun Xu, Dan Wang, Yuewei Zhang, Shoujun Zhu   +6 more
wiley   +1 more source

Functional characterization of 16 variants found in the LDL receptor gene

Journal of Lipid Research
Familial hypercholesterolemia (FH) is a disorder of cholesterol metabolism characterized by elevated LDL-cholesterol levels. The most common cause of FH is pathogenic variants in the LDL receptor (LDLR) gene.
Kateřina Konečná, Tereza Přerovská, Tomáš Loja, Lenka Fajkusová, Jana Koutná, Michal Kramárek, Ana Catarina Alves, Mafalda Bourbon, Tomáš Freiberger, Lukáš Tichý   +9 more
doaj   +1 more source

Lipid transfer protein-catalyzed exchange of cholesteryl ester between high density lipoproteins and apoB-containing lipoproteins

Journal of Lipid Research, 1987
Low density lipoproteins (LDL), lipoprotein (a)(Lp(a)), and lipoprotein(a) after removal of the a-protein (Lp(a-)) were compared with respect to their ability to accept cholesteryl ester from high density lipoproteins (HDL).
J E Groener, G M Kostner
doaj   +1 more source