Results 291 to 300 of about 462,380 (329)

Circulating low density lipoprotein (LDL)

Hormone Molecular Biology and Clinical Investigation, 2018
Abstract Low-density lipoprotein (LDL) particles are known as atherogenic agents in coronary artery diseases. They modify to other electronegative forms and may be the subject for improvement of inflammatory events in vessel subendothelial spaces. The circulating LDL value is associated with the plasma PCSK-9 level. They internalize into
Mohsen, Khosravi, Reza, Hosseini-Fard, Mohammad, Najafi   +2 more
openaire   +2 more sources

Oxidized Low-Density Lipoprotein (ox-LDL) to LDL Ratio (ox-LDL/LDL) and ox-LDL to High-Density Lipoprotein Ratio (ox-LDL/HDL):

Clinical Laboratory, 2016
Oxidized low-density lipoprotein (ox-LDL) plays a principal role in diabetes complications, though ox-LDL concentrations and its functions are dependents of other oxidative and anti-oxidative particles. The oxLDL to low-density lipoprotein ratio (ox-LDL/LDL) and ox-LDL to high-density lipoprotein ratio (ox-LDL/HDL) as new lipid biomarkers may serve as ...
Mahtab, Motamed, Arash A, Nargesi, Behnam, Heidari, Hossein, Mirmiranpour, Alireza, Esteghamati, Manouchehr, Nakhjavani   +5 more
openaire   +2 more sources

Low-density lipoprotein (LDL) oxidizability before and after LDL apheresis

Metabolism, 1999
Oxidation of low-density lipoprotein (LDL) plays a major role in the development of atherosclerosis. Hypercholesterolemia has been associated with enhanced in vitro oxidation of LDL, and lipid-lowering therapy reduces LDL oxidizability. In the present study, we investigated whether LDL apheresis performed with different techniques affects in vitro ...
M G, Donner, K G, Parhofer, W O, Richter, P, Schwandt   +3 more
openaire   +2 more sources

A New Low Density Lipoprotein (LDL) Adsorbent

Artificial Cells, Blood Substitutes, and Biotechnology, 1997
Crosslinked O-Carboxymethyl (O-CM) Chitosan beads were prepared by the reaction of O-CM Chitosan with glutaraldehyde solution. Results in vitro experiments with this new developed LDL adsorbent are presented. This adsorbent is capable of cutting down LDL-Cholesterol without significantly affecting HDL and TP (Total Proteins) levels in the plasma.
Y U, Yihua, H E, Binglin
openaire   +2 more sources

Are ‘precipitated LDL’ really low density lipoproteins?

Clinica Chimica Acta, 1987
Cholesterol, phospholipid and Apo B levels were determined in low density lipoproteins (LDL) precipitated by amphipathic polymers (Biomérieux kit, Marcy-l'Etoile, France) and compared to those of ultracentrifuged LDL. For 113 sera (triglyceride level less than 4.5 mmol/l, absence of very low density lipoproteins-remnants) LDL-cholesterol values were ...
F, Mainard, Y, Madec
openaire   +2 more sources

Low density lipoprotein (LDL) binding affinity for the LDL receptor in hyperlipoproteinemia

Atherosclerosis, 1999
We measured the binding affinity of low density lipoprotein (LDL) for the LDL receptor in patients with various types of hyperlipoproteinemia and investigated the effects of LDL lipid composition and particle size on receptor affinity. LDL (1.019 < d < 1.063) was isolated by sequential ultracentrifugation from the serum of normolipidemic controls and ...
Y, Toyota, T, Yamamura, Y, Miyake, A, Yamamoto   +3 more
openaire   +2 more sources

Autoantibodies against oxidized low-density lipoprotein (ox-LDL) and LDL oxidation status

Clinical Chemistry and Laboratory Medicine (CCLM), 2004
AbstractOxidized low-density lipoproteins (ox-LDLs) and their autoantibodies (OLAB) are involved in the development of atherosclerosis in animal models, but their role in humans is still not clear. For this reason we studied 54 patients with β-thalassemia major (TM), as a model of chronically low circulating LDLs with a high level of oxidation; 44 ...
Brizzi P, Tonolo G, Bertrand G, Carusillo F, Severino C, Maioli M, MALAGUARNERA, Lucia, Musumeci S.   +7 more
openaire   +3 more sources

Atorvastatin and simvastatin in patients on hemodialysis: effects on lipoproteins, C-reactive protein and in vivo oxidized LDL.

JN. Journal of Nephrology (Milano. 1992), 2003
BACKGROUND Cardiovascular disease as a result of accelerated atherogenesis is common in patients with end-stage renal disease (ESRD). Dyslipidemia may be a major contributor in this process and can be influenced by lipid-lowering drugs (statins ...
J. M. van den Akker, S. Bredie, S. Diepenveen, L. V. van Tits, A. Stalenhoef, R. van Leusen   +5 more
semanticscholar   +1 more source

Lipoprotein correlates of LDL particle size

Atherosclerosis, 2000
Correlations of low-density lipoprotein (LDL) predominant particle diameters (PPD) were investigated in samples taken from the San Antonio Family Heart Study. A frequency histogram showed LDL PPD occurs in at least two distinct modes, at about 25.5 and 26.9 nm, with the nadir at about 26.2 nm.
openaire   +2 more sources

LDL receptor-independent and -dependent uptake of lipoproteins

Atherosclerosis, 1995
The liver plays a decisive role in the regulation of the plasma levels of atherogenic lipoproteins. The primary liver interaction site for chylomicron-remnants and VLDL remnants (beta-VLDL) is still unidentified, while the subsequent cellular uptake is likely to be mediated in concert by the LDL receptor related protein (LRP) and the LDL receptor.
van Berkel, T. J., Fluiter, K., van Velzen, A. G., Vogelezang, C. J., Ziere, G. J.   +4 more
openaire   +3 more sources