Results 221 to 230 of about 67,544 (271)

Increased transvascular retention of atherogenic lipoproteins in type 2 diabetes relates to their enhanced proteoglycan binding. [PDF]

JCI Insight
Björklund P, Härdfeldt J, Äikäs L, Straniero S, Holopainen M, Öörni K, Rudling M, Angelin B.   +7 more
europepmc   +1 more source

Heart failure etiology and lipoprotein subfractions: Insight from the SMARTEX-HF study. [PDF]

Int J Cardiol Heart Vasc
Karlsen T, Vesterbekkmo EK, Hole T, Larsen AI, Valborgland T, Braaten T, Bathen TF, Beckers P, Delagardelle C, Feiereisen P, Craenenbroeck EV, Linke A, Prescott E, Halle M, Ellingsen Ø, Dalen H.   +15 more
europepmc   +1 more source

A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins. [PDF]

Elife
Kelpsch DJ, Zhang L, Thierer JH, Rivera Cruz AG, Koren K, Kumar U, Lin Y, Hensley MR, Sohn M, Liu JO, Lectka T, Mumm JS, Farber SA.   +12 more
europepmc   +1 more source

[Do very low density lipoproteins (VLDL) participate in atherogenesis?].

Kardiologia polska, 1992
openaire   +1 more source

Gene expression and intracellular pathways involved in endothelial dysfunction induced by VLDL and oxidised VLDL

Cardiovascular Research, 2003
Objectives: The molecular mechanisms underlying the relationship between elevated plasma concentrations of triglyceride-rich lipoproteins and coronary artery disease remain uncertain.
Angela Pirillo, Per Eriksson, Giuseppe Danilo Norata   +2 more
exaly   +2 more sources

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Heparin binding triggers human VLDL remodeling by circulating lipoprotein lipase: Relevance to VLDL functionality in health and disease

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2022
Hydrolysis of VLDL triacylglycerol (TG) by lipoprotein lipase (LpL) is a major step in energy metabolism and VLDL-to-LDL maturation. Most functional LpL is anchored to the vascular endothelium, yet a small amount circulates on TG-rich lipoproteins. As circulating LpL has low catalytic activity, its role in VLDL remodeling is unclear. We use pre-heparin
Jayaraman, S, Perez, A, Minambres, I, Sanchez-Quesada, JL, Gursky, O   +4 more
openaire   +3 more sources

Role of lipoprotein lipase separated from VLDL during VLDL catabolism

Biochemical and Biophysical Research Communications, 1982
Abstract Lipoprotein lipase (LPL) which is associated with very low density lipoprotein (VLDL) separated from the VLDL-LPL complex during hydrolysis of triglyceride in the presence of HDL in vitro. When further VLDL was added to the mixture, the separated LPL became associated with the freshly added VLDL and hydrolyzed its triglyceride. These results
N, Matsuoka, K, Shirai, Y, Saito, A, Kumagai   +3 more
openaire   +2 more sources

Influence of lipoprotein lipase and hepatic lipase on the transformation of VLDL and HDL during lipolysis of VLDL

Atherosclerosis, 1995
In order to study the relative effects of lipolytic enzymes on the removal of lipids and apolipoproteins, in particular apolipoprotein (apo) E and cholesteryl ester, from human very low density lipoprotein (VLDL) during its conversion to product lipoproteins, the action of lipoprotein lipase (LPL) and the combined action of lipoprotein lipase and ...
S J, Murdoch, W C, Breckenridge
openaire   +2 more sources

Ex vivo measurement of lipoprotein lipase-dependent very low density lipoprotein (VLDL)-triglyceride hydrolysis in human VLDL: an alternative to the postheparin assay of lipoprotein lipase activity?

The Journal of clinical endocrinology and metabolism, 2001
The plasma lipolysis of triglyceride (TG)-rich lipoproteins is mainly due to the activity of lipoprotein lipase (LPL). Albeit important for our analysis of certain physiopathological situations, the determination of the magnitude of LPL-dependent lipolysis is not easy to perform.
V, Pruneta, D, Autran, G, Ponsin, C, Marcais, L, Duvillard, B, Verges, F, Berthezene, P, Moulin   +7 more
openaire   +3 more sources

Effect of probucol on the composition of lipoproteins and on VLDL apoprotein B turnover

Atherosclerosis, 1983
We studied the effect of probucol on lipoprotein composition and VLDL apo B turnover. In 7 hypercholesterolemic subjects, probucol therapy lowered mean total cholesterol, HDL cholesterol and HDL triglycerides, raised LDL triglycerides and did not change LDL cholesterol. LDL cholesterol:LDL triglycerides mass ratios fell.
D R, Lock, I, Kuisk, B, Gonen, W, Patsch, G, Schonfeld   +4 more
openaire   +2 more sources