Results 41 to 50 of about 284,504 (254)

Role of apolipoprotein C1 in lipoprotein metabolism, atherosclerosis and diabetes: a systematic review

Cardiovascular Diabetology, 2022
Apolipoprotein C1 (apoC1) is a small size apolipoprotein whose exact role is not totally clarified but which seems to modulate significantly the metabolism of lipoproteins.
Alexia Rouland, David Masson, Laurent Lagrost, Bruno Vergès, Thomas Gautier, Benjamin Bouillet   +5 more
doaj   +1 more source

HDL and plaque regression in a multiphase model of early atherosclerosis [PDF]

, 2023
Atherosclerotic plaques are accumulations of cholesterol-engorged macrophages in the artery wall. Plaque growth is initiated and sustained by the deposition of low density lipoproteins (LDL) in the artery wall. High density lipoproteins (HDL) counterbalance the effects of LDL by accepting cholesterol from macrophages and removing it from the plaque. In
arxiv   +1 more source

CLA-1 is an 85-kD plasma membrane glycoprotein that acts as a high-affinity receptor for both native (HDL, LDL, and VLDL) and modified (OxLDL and AcLDL) lipoproteins.

Arteriosclerosis, Thrombosis and Vascular Biology, 1997
Lipoprotein metabolism is regulated by the functional interplay between lipoprotein components and the receptors and enzymes with which they interact.
D. Calvo, D. Gómez-Coronado, M. A. Lasunción, M. Vega   +3 more
semanticscholar   +1 more source

LPS-binding protein circulates in association with apoB-containing lipoproteins and enhances endotoxin-LDL/VLDL interaction.

Journal of Clinical Investigation, 2001
LPS-binding protein (LBP) and serum lipoproteins cooperate in reducing the toxic properties of LPS. In the present study, we demonstrate that LBP circulates in association with LDL and VLDL in healthy persons.
Anita C.E. Vreugdenhil, A. Snoek, Cornelis van 't Veer, J. Greve, Wim A. Buurman   +4 more
semanticscholar   +1 more source

The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor. [PDF]

Journal of Clinical Investigation, 1997
Lp(a) is a major inherited risk factor associated with premature heart disease and stroke. The mechanism of Lp(a) atherogenicity has not been elucidated, but likely involves both its ability to influence plasminogen activation as well as its atherogenic potential as a lipoprotein particle after receptor-mediated uptake.
Karen Kozarsky, John T. Fallon, Kelley M. Argraves, Dudley K. Strickland, Peter C. Harpel   +4 more
openaire   +3 more sources

Very Low Density Lipoprotein (VLDL) Receptor-deficient Mice Have Reduced Lipoprotein Lipase Activity [PDF]

Journal of Biological Chemistry, 2002
Although very low density lipoprotein (VLDL) receptor (VLDLr) knockout mice have been reported to have no lipoprotein abnormalities, they develop less adipose tissue than control mice when fed a high calorie diet. Mice that are deficient in adipose tissue expression of lipoprotein lipase (LpL) also have less fat, but only when crossed with ob/ob mice ...
Sungshin Y. Choi, E. Peer Lutz, André Bensadoun, Yuko Kako, Hiroaki Yagyu, Yunying Hu, Ira J. Goldberg, Steven A. Marks   +7 more
openaire   +3 more sources

Causal Models with Constraints [PDF]

arXiv, 2023
Causal models have proven extremely useful in offering formal representations of causal relationships between a set of variables. Yet in many situations, there are non-causal relationships among variables. For example, we may want variables $LDL$, $HDL$, and $TOT$ that represent the level of low-density lipoprotein cholesterol, the level of lipoprotein
arxiv  

A comparative study of the lipid panel levels at different duration time and temperature storage [PDF]

arXiv, 2023
Background: the stability of serum specimen during time storage is importance in clinical and medical science researches in addition of diagnosis. Lipids are organic molecules that classified into 8 classes: fatty acids, phospholipids, glycerolipids, saccharolipids, polyketides, prenol lipids, sterol, and sphingolipids.
arxiv  

Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL [PDF]

Journal of Lipid Research, 1998
Mouse and hamster SR-BI glycoproteins and their putative human counterpart CLA-I are so far the only scavenger receptors known to bind both native and modified lipoproteins. CD36, a multigland glycoprotein structurally related to SR-BI and CLA-1, has been reported to bind oxidized low density lipoprotein (OxLDL) and acetylated LDL (AcLDL).
Miguel A. Vega, Miguel A. Lasunción, Diego Gómez-Coronado, Yajaira Suárez, Dominica Calvo   +4 more
openaire   +4 more sources

Residual Risk of Atherosclerotic Cardiovascular Events in Relation to Reductions in Very‐Low‐Density Lipoproteins

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017
Background It is uncertain whether pharmacological reductions in very‐low‐density lipoproteins (VLDLs), and their component triglyceride and cholesterol could reduce residual risk of atherosclerotic cardiovascular disease (ASCVD) events among individuals
P. Lawler, A. Akinkuolie, Paulo H. Harada, R. Glynn, D. Chasman, P. Ridker, S. Mora   +6 more
semanticscholar   +1 more source