Results 61 to 70 of about 572,907 (380)

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source

Increased fluidity and oxidation of malarial lipoproteins: relation with severity and induction of endothelial expression of adhesion molecules

Lipids in Health and Disease, 2004
Introduction Oxidative stress has been demonstrated in malaria. The potential oxidative modification of lipoproteins derived from malaria patients was studied. These oxidized lipids may have role in pathogenesis of malaria.
Looareesuwan Sornchai, Brittenham Gary, Leowattana Wattana, Krudsood Srivicha, Yamanont Paveena, Sibmooh Nathawut, Udomsangpetch Rachanee   +6 more
doaj   +1 more source

Glycomic analysis of high density lipoprotein shows a highly sialylated particle. [PDF]

, 2014
Many of the functional proteins and lipids in high density lipoprotein (HDL) particles are potentially glycosylated, yet very little is known about the glycoconjugates of HDL.
German, J Bruce, Huang, Jincui, Lebrilla, Carlito B, Lee, Hyeyoung, Rivera, Nancy, Smilowitz, Jennifer T, Zivkovic, Angela M   +6 more
core   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Comparative investigation on the sizes and scavenger receptor binding of human native and modified lipoprotein particles with atomic force microscopy

Journal of Nanobiotechnology, 2018
Background The size and receptor-binding abilities of plasma lipoproteins are closely related with their structure/functions. Presently, the sizes of native lipoproteins have been measured by various methods including atomic force microscopy (AFM ...
Chaoye Gan, Kun Wang, Qisheng Tang, Yong Chen   +3 more
doaj   +1 more source

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles. [PDF]

, 2017
Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma.
Alderete, Benjamin, Amento, Edward P, Kong, Raymond, Liu, David, Lundry, Jason, Madasamy, Shanmugavel, Robinson, J Paul, Wu, Alan HB   +7 more
core   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Lipoprotein metabolism in the suckling rat: characterization of plasma and lymphatic lipoproteins.

Journal of Lipid Research, 1983
Suckling rat plasma contains (in mg/dl): chylomicrons (85 +/- 12); VLDL (50 +/- 6); LDL (200 +/- 23); HDL1 (125 +/- 20); and HDL2 (220 +/- 10), while lymph contains (in mg/dl): chylomicrons (9650 +/- 850) and VLDL (4570 +/- 435) and smaller amounts of ...
G J Fernando-Warnakulasuriya, M L Eckerson, W A Clark, M A Wells   +3 more
doaj   +1 more source

Study of the correlations between serum iron and Hepcidin with some biochemical variables in hyperlipidemia of elderly males and females in Salah Al Deen Province

Tikrit Journal of Pure Science, 2020
The present research was designed to investigate the role of the relationship between Iron and hepcidin hormon with some biochemical variables in patients with hyperlipidemia in both males and females elderly in Salah al-Din governorate.
Khalida Khalil Abdullah, Saleh Mohammed Rahim   +1 more
doaj   +1 more source

Moderate exercise increases affinity of large very low density lipoproteins for hydrolysis by lipoprotein lipase [PDF]

, 2015
Context: Postprandial triglyceride (TG) concentration is independently associated with cardiovascular disease risk. Exercise reduces postprandial TG concentrations but the mechanisms responsible are unclear.
Bedford, Dorothy K., Caslake, Muriel J., Cooney, Josephine, GHAFOURI, Khloud, Gill, Jason M.R., Wilson, John   +5 more
core   +1 more source