Results 231 to 240 of about 183,250 (346)

SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy

open access: yesAdvanced Science, EarlyView.
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong   +9 more
wiley   +1 more source

Innovative liposomal coumarin: A promising solution for enhancing soft white cheese quality. [PDF]

open access: yesPLoS One
Alqaraleh S   +6 more
europepmc   +1 more source

DNA Origami‐Based CD44‐Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression

open access: yesAdvanced Science, EarlyView.
This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv   +8 more
wiley   +1 more source

Photoinduced Electron Transfer Across Phospholipid Bilayers in Anaerobic and Aerobic Atmospheres. [PDF]

open access: yesAngew Chem Int Ed Engl
Sinambela N   +4 more
europepmc   +1 more source

Precision‐Guided Stealth Missiles in Biomedicine: Biological Carrier‐Mediated Nanomedicine Hitchhiking Strategy

open access: yesAdvanced Science, EarlyView.
Diagram illustrating the binding methods of NPs and biological barriers. The biological carrier‐mediated nanomedicine hitchhiking strategy (BCM‐NHS) utilizes two distinct techniques: the surface‐based “Backpack” method, which relies on ligand‐receptor binding, covalent conjugation, and non‐covalent binding, and the encapsulated “Trojan horse” approach,
Yuyan Zhou   +17 more
wiley   +1 more source

A protease-cleavable liposome for co-delivery of anti-PD-L1 and doxorubicin for colon cancer therapy in mice. [PDF]

open access: yesNat Commun
Liu Y   +17 more
europepmc   +1 more source

Enhanced and Durable Light‐Driven Hydrogen Evolution by Cobalt‐Based Prussian Blue Analogs in Phospholipid Bilayers

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
Light‐driven H2 evolution catalysis is reported for oleylamine‐capped MCo Prussian blue analogs (PBAs, M = Ni, Co, Zn, Cu) within phospholipid bilayers and using a ruthenium‐based amphiphilic photosensitizer. The hydrophobic interactions between the active units bring them in close proximity facilitating catalysis.
Subrata Mandal   +5 more
wiley   +1 more source

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