Emerging liposomal therapies for diabetic retinopathy: a review of novel targeting approaches and advances in retinal health outcomes. [PDF]
Parashar R, Suresh PK.
europepmc +1 more source
Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu+7 more
wiley +1 more source
Study on the Pharmacological Efficacy and Mechanism of Dual-Target Liposome Complex AD808 Against Alzheimer's Disease. [PDF]
Liu C+6 more
europepmc +1 more source
Bacterial Minicell‐Based Biohybrid Sub‐micron Swimmers for Targeted Cargo Delivery
Bacterial minicells, vesicles derived from engineered E. coli, offer promising sub‐micron scale biohybrid swimmers for targeted cargo delivery. Purified with over 99% efficiency while retaining motility, they are functionalized with MNPs for controlled movement.
Saadet Fatma Baltaci+4 more
wiley +1 more source
Nanomaterials Trigger Functional Anti‐Tumoral Responses in Primary Human Immune Cells
Nanoparticles are used to improve immunomodulatory therapies, but the impact of drug‐free nanomaterials on the immune system remains unknown. Screening common biomedical nanoparticles (NPs) reveals that PLGA NPs enhanced NK cell anti‐tumoral activity and transcriptional activation in human NK and pan T cells.
Vincent Mittelheisser+20 more
wiley +1 more source
Preparation, Conformational Structure, and Proteolytic Activity of Papain Covalently Conjugated to Poly(ethylene glycol)-Tethered Lipid Bilayer Membranes. [PDF]
Takahashi Y+3 more
europepmc +1 more source
The Role of CAF‐derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression
Cancer‐associated fibroblast (CAF)‐derived VTN upregulates SLC6A8 expression in colorectal cancer (CRC) cells and macrophages through enhanced FAK phosphorylation. This modulation significantly increases the cellular uptake of creatine and ATP, promoting cancer progression and macrophage polarization.
Jiahua Yu+5 more
wiley +1 more source
Matrix Metalloproteinase-2-Responsive Peptide-Modified Cleavable PEGylated Liposomes for Paclitaxel Delivery. [PDF]
Zhao X, Li Y.
europepmc +1 more source
Metabolic Programming Drives Protective and Inflammatory Monocyte Fates in Viral Encephalitis
Bone marrow monocytes infiltrate the West Nile virus‐infected brain and differentiate into HIF1‐α⁺ monocyte‐derived cells (MCs) that diverge into protective, antigen‐presenting or inflammatory, iNOS⁺ MCs with distinct metabolic programs and functions.
Claire L. Wishart+4 more
wiley +1 more source