Results 191 to 200 of about 147,676 (314)

Mitochondria-TargetedPolymeric Liposomes for Pre-miRNAImaging and Gene Therapy

Xiangdan Meng (3371456), Junyan Yang (11213952), Sirong Sun (14310797), Yijie Gao (4630462), Zhou Yang (329522), Haifeng Dong (392234), Xueji Zhang (392238)   +6 more
openalex   +1 more source

Universal Antibody‐Engineered Lipid Nanoparticles Potentiate Chemo‐Immunotherapy Against Triple‐Negative Breast Cancer by Reprogramming Tumor Cell Metabolism

Advanced Science, EarlyView.
A universal ROR1 antibody‐engineered lipid nanoparticle (LNP) is constructed by sequential drug encapsulation and antibody conjugation. The LNP not only enables enhanced chemotherapeutic efficiency by targeting drug delivery and precise localization of deep‐seated tumors through NIR‐II fluorescence imaging, but also remodels immunosuppressive TME ...
Yeneng Dai, Jiaqi Wang, Yu Liu, Guanda Jiao, Yuheng Gu, Yang Liu, Shengyu Fu, Xing Fan, Jialin Li, Ziang Guo, Kam Tong Leung, Lipeng Zhu, Qi Zhao   +12 more
wiley   +1 more source

Liposomal Delivery of Pyronaridine as a Repurposed Inhibitor of ERCC1/XPF for the Sensitization of Colorectal Cancer Cells to Platinum Chemotherapeutics. [PDF]

Mol Pharm
Mehinrad P, Abdelfattah A, Shafaati T, Emami J, Donnelly J, West FG, Weinfeld M, Lavasanifar A.   +7 more
europepmc   +1 more source

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

Advanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu, Jie Yu, Jingxue Li, Yixue Chen, Mengle Peng, Yifan Xu, Yongjun Wu, Lihua Ding, Sitian He   +8 more
wiley   +1 more source

Changes in Resveratrol Containing Phytosterol Liposomes During Model Heating. [PDF]

Molecules
Igielska-Kalwat J, Rudzińska M, Grygier A, Kmiecik D, Cieślik-Boczula K, Tomaszewska-Gras J.   +5 more
europepmc   +1 more source

<p>Transferrin-Modified Osthole PEGylated Liposomes Travel the Blood-Brain Barrier and Mitigate Alzheimer’s Disease-Related Pathology in APP/PS-1 Mice</p>

, 2020
Liang Kong, Xuetao Li, Yingnan Ni, Honghe Xiao, Yingjia Yao, Yuan-yuan Wang, Rui-Jun Ju, Hongyan Li, Jingjing Liu, Min Fu, Yutong Wu, Jingxian Yang, Lan Cheng   +12 more
openalex   +2 more sources

Intelligent Thermo‐Self‐Limited Magnetothermia with Heat‐Triggered TERT Silencing for Precision Synergetic Cancer Therapy

Advanced Science, EarlyView.
Telomerase reverse transcriptase (TERT) mRNA induces DNA self‐assembly in cancer cells, boosting the nanoplatform's magnetothermal properties. This magnetothermia then activates the Hsp70 promoter, initiating siRNA synthesis to silence the TERT gene, enhancing cancer treatment.
Liang Zhang, Mingfu Gong, Tao Sun, Shilin Xiao, Yue Zhao, Xiaofeng Yang, Wansu Zhang, Chunyu Zhou, Xu Liu, Dong Zhang   +9 more
wiley   +1 more source

Anidulafungin liposome nanoparticles exhibit antifungal activity against planktonic and biofilm Candida albicans

, 2020
Noel Vera‐González, Christina M. Bailey‐Hytholt, Luc Langlois, Felipe de Camargo Ribeiro, Evelyn Luzia de Souza Santos, Juliana Campos Junqueira, Anita Shukla   +6 more
openalex   +2 more sources

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

Advanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang, Xuxi Chen, Hongying Quan, Rui Qian, Shuyu Gong, Qiurong He, Ying Gao, Ajia Axi, Manyu Zhao, Qin Zhang, Ling Zhang, Lijun Peng, Xin Sun, Ben Zhang, Yuqin Yao   +14 more
wiley   +1 more source

Comparative Analysis of Sonication, Microfluidics, and High-Turbulence Microreactors for the Fabrication and Scaling-Up of Diclofenac-Loaded Liposomes. [PDF]

Pharmaceutics
Naveira-Souto I, Fabrega Alsina R, Rosell-Vives E, Pena-Rodríguez E, Fernandez-Campos F, Malavia J, Julia Camprodon X, Schelden M, Günday-Türeli N, Cruz-Conesa A, Lajarin-Reinares M.   +10 more
europepmc   +1 more source