Results 281 to 290 of about 338,765 (389)

NDRG1‐Driven Lactate Accumulation Promotes Lung Adenocarcinoma Progression Through the Induction of an Immunosuppressive Microenvironment

Advanced Science, EarlyView.
NDRG1 drives lactate accumulation and histone lactylation in lung adenocarcinoma, promoting immunosuppression via M2 macrophage polarization and CD8⁺ T cell inhibition. High NDRG1 expression correlates with poor prognosis, an immunosuppressive microenvironment, and immunotherapy resistance.
Gujie Wu, Hongxia Cheng, Jiacheng Yin, Yuansheng Zheng, Haochun Shi, Binyang Pan, Ming Li, Mengnan Zhao, Jiaqi Liang, Yunyi Bian, Guangyao Shan, Guoshu Bi, Weigang Guo, Lin Wang, Yiwei Huang   +14 more
wiley   +1 more source

Nano-Liposomal Carrier as Promising Dermal Delivery Platform for <i>Fumaria officinalis</i> L. Bioactives. [PDF]

Pharmaceutics
Ahmoda RA, Milošević M, Marinković A, Jovanović AA.   +3 more
europepmc   +1 more source

NaCl-induced aggregation of egg phosphatidylcholine liposomes.

, 1986
Mariko Nagata, Toshihisa Yotsuyanagi, Ken‐ichi Ikeda   +2 more
openalex   +2 more sources

RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang, Shengtao Cheng, Huiying Gu, Shan Zhong, Dapeng Zhang, Xin He, Weixian Chen, Haijun Deng, Jihua Ren, Peng Chen, Ming Tan, Hui Zhang, Fan Li, Zhenzhen Zhang, Yuan Hu, Juan Chen   +15 more
wiley   +1 more source

Novel (1S,3R)-RSL3-Encapsulated Polyunsaturated Fatty Acid Rich Liposomes Sensitise Multiple Myeloma Cells to Ferroptosis-Mediated Cell Death. [PDF]

Int J Mol Sci
Habib A, Mynott RL, Best OG, Revesz IA, Prestidge CA, Wallington-Gates CT.   +5 more
europepmc   +1 more source

Interaction of the Marine Humic Acid with Liposomes

, 1982
Shigeo Hayano, N. Shinozuka, Y. Ikenoue
openalex   +2 more sources

Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes

FEBS Letters, 1990
A. Klibanov, K. Maruyama, V. Torchilin, Leaf Huang   +3 more
semanticscholar   +1 more source

Remodeling the Physicochemical and Pharmacokinetic Properties of PROTAC via Lipid Nanodisks for Cancer Therapy

Advanced Science, EarlyView.
To solve the challenge of PROTACs in clinical potential due to poor water solubility and membrane permeability, a nanodelivery system based on lipid nanodisks loaded with MZ1 prodrug (LND‐MZ1) to remodel the physicochemical and pharmacokinetic properties of PROTAC MZ1 is elaborately proposed.
Meichen Pan, Chunrong Yang, Zhongliang Fu, Yuchen Yang, Ying Zhuo, Hongwei Hou, Jinghong Li   +6 more
wiley   +1 more source

pH-Sensitive Multiliposomal Containers for Encapsulation and Rapid Release of Bioactive Substances. [PDF]

Molecules
Efimova AA, Abramova TA, Yatsenko IV, Kazantsev AV, Pozdyshev DV, Lukashev NV, Muronets VI, Yaroslavov AA.   +7 more
europepmc   +1 more source