Results 281 to 290 of about 244,267 (315)

Multifunctional Framework Nucleic Acid Vehicle for Antibiotic Sensitization and Treatment of Methicillin‐Resistant Staphylococcus aureus

open access: yesAggregate, EarlyView.
A self‐assembling, aggregation‐enhanced tetrahedral DNA nanostructure (tFNA), termed TACs, enables localized accumulation and sustained release of ceftriaxone while co‐delivering antisense oligonucleotides that silence mecA, reduce PBP2a expression, and restore β‐lactam susceptibility in MRSA.
Yicheng Zhao   +10 more
wiley   +1 more source

Purified prion proteins and scrapie infectivity copartition into liposomes.

open access: green, 1987
Ruth Gabizon   +2 more
openalex   +1 more source

Immunostimulatory DNA Tetrahedron‐Based Nanovaccine Combined With Immune Checkpoint PD‐1 Blockade for Boosting Systemic Immune Responses Against Oral Squamous Cell Carcinoma

open access: yesAggregate, EarlyView.
This study introduces an immunomodulatory DNA tetrahedral framework nucleic acid‐based nanovaccine tFNA‐CpG. The functionalized nanovaccine shows stable and well‐defined morphological characteristics and can be efficiently taken up by APCs. When combined with the immune checkpoint inhibitor anti‐PD‐1, it notably ameliorated the immunosuppressive ...
Xueting Yang   +12 more
wiley   +1 more source

PEGylated Liposomes of Disulfiram and Paclitaxel: A Promising Chemotherapeutic Combination Against Chemoresistant Breast Cancer. [PDF]

open access: yesPharmaceuticals (Basel)
Said Suliman A   +8 more
europepmc   +1 more source

Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications

open access: yesAdvanced Intelligent Systems, EarlyView.
Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu   +4 more
wiley   +1 more source

circNR3C2 promotes chondrogenic differentiation and cartilage repair of human adipose‐derived stem cells via the hsa‐miR‐647/SOX9 pathway

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy